An alternative synthesis of Azilsartan: an angiotensin II receptor blocker
Journal Title: Current Issues in Pharmacy and Medical Sciences - Year 2015, Vol 28, Issue 2
Abstract
This paper provides a description of an alternative, novel and commercially viable process which has been developed for the preparation of Azilsartan, a pro-drug of Azilsartan medoxomil, an angiotensin II receptor blocker. The present work also provides a primary account of the synthesis and characterization of the novel intermediates (6, 7 & 10) of Azilsartan, with their spectral data.
Impact of the grasping test on women’s cardiovascular systems, and the possibility of replacing the orthostatic tolerance test with it
The aim of this study was to test the impact of the Grasping Test (GT) on the female cardiovascular system and to ascertain the possibility of using this to replace the Orthostatic Tolerance Test (OT). In this study, 15...
Determination of caffeic acid in root and rhizome of Black cohosh (Cimicifuga racemosa (L.) Nutt).
Cimicifuga racemosa, is a plant with a diverse and long history of medicinal use. Caffeic acid, bioactive compound, which often occurs with other polyphenols can influence the biological activity of this plant. The aim o...
Comparative validation of HPLC, densitometric and videodensitometric determination of lamotrigine in pharmaceutical
Simple, sensitive, precise and accurate HPLC, densitometric and videodensitometric methods for determination of lamotrigine in tablet forms were developed and validated. The HPLC method was carried out using a Symmetry C...
The influence of selected demographic and socioeconomic factors on patient’s decision-making about the treatment of missing teet
The research aimed at assessment of the influence of selected demographic and socioeconomic factors on patient's decision-making about the treatment of missing teeth using the implants. The survey was conducted among 46...
Quantitative analysis of biofilm formation by oropharyngeal Candida albicans isolates under static conditions by confocal
Candida albicans may colonize natural or artificial surfaces, leading to formation of the biofilm. Infections associated with the biofilm formation are important therapeutic problem. In this paper, we present data concer...