An impact of Mardana- A comperative study on Arogyavardhini Rasa
Journal Title: The Journal of Phytopharmacology - Year 2016, Vol 5, Issue 6
Abstract
Background: Arogyavardhini Rasa (AVR); a Kharaliya Rasakalpa containing rasavarga dravya (metallomineral ingredients) is widely used Ayurvedic herbo-mineral formulation having broad spectrum therapeutic indications. Current research is first effort to scientifically document quality control parameters of this important formulation. Aim: To establish a comparative pharmaceutico - analytical profile of AVR prepared with and without its metallomineral ingredients. Materials & Methods: Arogyavardhini Rasa (AVR) and modified Arogyavardhini Rasa (MAVR) without addition of its metallomineral ingredients were prepared and investigated for Physico-chemical parameters, qualitative tests for functional groups, Chromatography, quantitative elemental analysis by ICP-AES. Results & Discussion: An average of 2500ml Swarasa was required for optimum Mardana in both formulations. HPTLC study revealed a total of 11 and 8 bands at 254nm and 366nm in each AVR and MAVR with only two similar Rf values. Samples AVR, MAVR and MAVR with addition of Rasa Dhatukajjali showed 1.5226, 0.0117 and 1.703 % of mercury respectively. Conclusion: Mardana play significant role in development of Kharaliya Rasakalpa Both the formulations showed different through physicochemical profiles and ICP-AES analysis. Differences in chromatographic fingerprinting of AVR and MAVR are suggestive of changes in chemical constituents of the formulation due to addition of metallo minerals.
Authors and Affiliations
Yuga Raj Sapkota, Prashant Bedarkar, Galib, V. J. Shukla, P. K. Prajapati
Keywords
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