AN OBJECTIVE MEASUREMENT OF COGNITIVE FUNCTIIONS: A COMPARATIVE STUDY BETWEEN PATIENTS WITH PARKINSON’S DISEASE & AGE MATCHED HEALTHY EGYPTIAN POPULATIAN
Journal Title: Academic Research International - Year 2018, Vol 9, Issue 2
Abstract
Objective: Cognitive impairemnt is an important feature in patients with parkinson’s diesease. Cognition is assessed through many validated psychometric batteries as Montreal cognitive assessment (MOCA) and Clinical Dementia Rating Scale (CDRs). Subjective nature of these batteries has an impact on their reliability. An objective measure of cognitive function minimizes this defect. Rehacom cognitive assessment is an objective way of cognitive assessment. Subjects and Methods: Twenty three male subjects ;twelve patients with parkinson’s disease and eleven normal age matched subjests participated in this study.the age ranged from 50 to 70 years old. Subjects were assessed by the MoCA and CDRs and rehacom device for attention and concentration and memory domains (attention level, minimum reaction time, median reaction time and maximum reaction time, while the varaibles of figural memory modules that were measured were memory level, acquisition time and solution time). This study is a cross section design. Results: A significant difference was found in CDRs scores, attention level, memory level and solution time between parkinsonian and normal group (P<0.004), (P<0.011), (P<0.004), (P<0.000). Conclusion: MOCA scores can detect objectively any decline in cognitive functions in patients with PD because there was a direct moderate correlation between it and rehacome scores .Also there is a decline in cognitive functions in patients with PD when measured objectively by rehacome and compared with healthy subjects of martched age. Also the mean average of cognitive functions in egyptians healthy subjects by MOCA scores is 25.36 ± 3.776 and rehacom (attention level is 6.55 +/- 1.214, memory level is 5.64± 1.286, solution time is 64.64± 8.640 s). the median CDRs score is 0.000, minimum reaction time is 4460.0000 ms, median reaction time is 6190.00 ms, maximum reaction time is 23740.0000 ms and acquisition time is 9.00 s.
Authors and Affiliations
Gehan M. Ahmed, Hanan A. Amer, Walaa M. Ragab, Nermin A. Salam, Ahmed A. Hassan
Keywords
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