An update on Anaemia, Iron, Folic acid and Vitamin B 12 in Pregnancy and Postpartum
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 5
Abstract
Anaemia is a decrease in number of red blood cell (RBCs) or less than the normal quality of haemoglobin in the blood. However, it can include decreased oxygen-binding ability of each haemoglobin molecule due to deformity or lack of numerical developments as in some other types of haemoglobin deficiency.Iron deficiency anaemia is the common cause of anaemia in women affecting 5-10 of women of child bearing age (20-44 years) and among pregnant women and postpartal, the prevalence of anaemia is up to 20-40%.Anaemia in pregnancy can be defined as haemoglobin concentration below 11g/dL. Anaemia in pregnancy is a common problem in most developing countries and a major cause of mortality and morbidity especially in malaria endemic areas. Low haemoglobin levels in pregnancy may lead to preterm delivery and low birth weight and increase in the risk of maternal mortality. During pregnancy, a woman’s iron requirement increase three fold to support the growth of the fetal placental unit and increased red cell mass. After it is absorbed across the maternal gut, iron is carried to the liver in the serum, iron is bound to transferrin. Transferrin has 2 iron binding sites with approximately equal affinities for iron. It is glycossylated and of interest, the glycosylation patterns change during pregnancy.
Authors and Affiliations
Obeagu Emmanuel Ifeanyi1 Obeagu Getrude Uzoma2
Keywords
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- EP ID EP563176
- DOI 10.22192/ijcrms.2018.04.05.010
- Views 127
- Downloads 0
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