Analysis of risk factors, clinical features and visual outcome in cases of non-arteritic anterior ischemic optic neuropathy (NA-AION) at a tertiary eye care centre in India
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 4
Abstract
We did an analysis of risk factors clinical features and visual outcome in cases of nonarteritic anterior ischemic optic neuropathy NAAION at a tertiary eye care centre in IndiaThis is a prospective observational clinical study A total of 60 eyes of 60 consecutive adult patients with disc oedema due to nonarteritic AION presenting in the Neuroophthalmology clinic of a tertiary care eye hospital were enrolled over a period of 18 months in specified period according to the inclusion criteriaThe study including patient recruitment and data collection was approved by the Institutional Review Board All patients provided written informed consent after they received information about the disease and its relevant investigations along with the risks associatedSample collection was done by application of inclusion and exclusion criteria on the patients presenting to the clinicThe study was carried out for a period of 6 months for each subject The major outcomes of the study wereMetabolic Syndromes are the most significantly associated risk factors for the occurrence of NA AIONClinical investigations mainly show the characteristic findings as mentioned in literature with very little variation However the importance of clinical examination mainly pupillary reaction and fundus evaluation by slit lamp biomicroscopy cannot be overlookedVisual acuity is highly variable at presentation with cases even presenting with normal or near normal visual acuity Visual outcome showed significantly improvement within 6 months of presentation Non arteritic anterior ischemic optic neuropathy NAION was the most common form of ischemic optic neuropathy in our studyIt is an idiopathic ischemic insult of the optic nerve head characterized by acute monocular painless visual loss with optic disc swellingThe systemic risk factor which we found to be most strongly associated with was diabetes mellitus followed by systemic hypertension Also an ocular risk factor of small cup size We have few inherent limitations in the study mainly with the occurrence of symptoms and time of presentation of the patient which may have a bearing on the final outcome of the disease Also a short follow up limited us regarding study of the stabilization of visual acuity over a longer durationHowever our study gives an overview of prevalent risk factors and clinical characteristics It also shows a significant visual outcome after 6 months in NAAIONKeywords Clinical features NA AION Visual outcome India
Authors and Affiliations
Aditya Vikram Sharma, Aditi Sharma
Keywords
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- EP ID EP474872
- DOI 10.18231/2395-1451.2018.0121
- Views 82
- Downloads 0
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