Analysis of Serum Lipoproteins, Apolipoproteins in Acute Viral Hepatitis Caused by HBV, HCV
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 1
Abstract
Introduction: Liver is the most important organ which is responsible for formation and clearance of Lipoproteins, Lipids, Apolipoproteins. Acute Viral hepatitis constitute most common among all hepatitis. Estimation of Changes in lipids, lipoproteins, apolipoproteins aid in diagnosis. Materials and Methods: All the patients were divided into two groups for a comparative study between Viral hepatitis patients and others without any sepsis. They are study group and control group. All patients blood sample has processed for routine examination of Liver function tests, Renal function test, Blood glucose, Detection of viruses, complete blood count, Peripheral smear, Blood coagulation status. HBV and HCV positive samples serum lipid profiles were compared with control subjects and tabulated. Results: Total Cholesterol (TC), High Density Lipoprotein - Cholesterol (HDL-C), Apolipoprotein A1, Apolipoprotein B levels shown lower levels in study group when compared to control group and in contrast Low Density Cholesterol - Cholesterol (LDL-C) and Triglycerides(TG's) shown higher levels in study group.Total Cholesterol, Triglycerides, HDL-C, LDL-C, Apolipoprotein A1, Apolipoprotein B levels were lower in acute phase than in recovering phase of viral hepatitis. Conclusion: Assessing this variations in lipidemic levels will help in diagnosing the acute viral hepatitis condition and helps in starting therapy towards prevention of cardiovascular diseases.
Authors and Affiliations
Sundara Veena Nethala, Geethanjali Anke
Keywords
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