Anemia in Type 2 Diabetes Mellitus (T2dm) and its association with vitamin B12 deficiency
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 1
Abstract
Introduction India is the diabetic capital of the world Vitamin B12 deficiency has been recognized since many years ago as an important side effect in diabetic patients who take metformin for more than 510 yearsThis research aimed to determine the prevalence of anemia in type 2 diabetes mellitus T2DM and its association with vitamin B12 deficiency due to use of MetforminMaterials and Methods Total 200 type 2 diabetes mellitus T2DM males and females were included in the studyBlood collection for Fasting blood glucose and Hba1c levels were measured from all participants in tubes without anticoagulant Hemoglobin mean corpuscular volume MCV were measured by automated cell counters Measurement of vitamin B12 level was done only in those patients who presented with Macrocytic anemiaResults Among 200 patients 113 patients were on vegetarian The prevalence of anemia in this study population was 65325 11169 were diagnosed as Normocytic Normochromic anemia 22 338 with Microcytic Hypochromic Anemia 2640 with Macrocytic Anemia and 692 with Dimorphic anemia Among these 32 patients who presented with macrocytic and dimorphic anemia vitamin B12 levels were measured For 23 vitamin B 12 level was200 pgml 149 patients were on MetforminConclusion Our findings suggest that correction of anemia may have a significant role in prevention of other diabetic complications thus we recommend that treatment criteria for diabetes should include routine hematological tests and annual screening of Vitamin B12 deficiency along with supplementation should be adopted while treating T2DMKeywords Macrocytic Anemia Type2 Diabetes Mellitus
Authors and Affiliations
Smriti Rathore, Prashant Kumar Singh, Anjana Kumar
Keywords
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- EP ID EP473182
- DOI 10.18231/2394-6792.2018.0010
- Views 58
- Downloads 0
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