Anti-diabetes and anti-obesity: A meta-analysis of different compounds
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2016, Vol 6, Issue 9
Abstract
Diabetes and obesity are chief health crisis and mainly age-related metabolic disorders. Diabetes is the main cause of morbidity and mortality worldwide. Obesity is linked with the progression of diabetes mellitus. High levels of glycerol, fatty acids, enzymes, proinflammatory markers and other obese entities build up insulin resistance in obese persons. The pathology of diabetes involves the dysfunction of β-islet cells of pancreas leading to deficient management of blood glucose level. This study demonstrates the anti-diabetic and anti-obesity effect of plant derived chemicals, some agonists, nutraceuticals, pharmaceutical drugs, some proteins and other compounds from 1998 to 2015. Plant derived from chemicals and other compounds were concluded to control diabetes and obesity by increasing number of glucose transporters, β-islet cells of pancreas, and lipid metabolism enzymes. In this way, the impairment of β-islet cells of pancreas is restored and the serum cholesterol and glucose levels of individuals are lowered. Further approaches are also needed to handle and cure diabetes and obesity.
DRESS syndrome caused by para-aminosalicylic acid: a case report and literature review
The aim of this study was to evaluate the reaction of the use of para-aminosalicylic acid (PAS). We reported the cases of multidrug-resistant tuberculosis treated with anti-tuberculosis therapy and PAS to develop drug ra...
Brucellosis: presence of zoonosis infection 3 500 years ago in North of Iran
Objective: To investigate the presence of brucellosis in graved human and animal buried in the same graves around 3 500 years ago. Methods: Two ancient graves in AH2XX1 trench in Gohar Tepe (Behshahr, North of Iran) in w...
Preventive and curative effect of methanolic extract of Gardenia gummifera Linn. f. on thioacetamide induced oxidative stress in rats
Objective: To evaluate the antioxidant and antihepatotoxic effect of methanolic extract of Gardenia gummifera Linn. f. root (MEGG) on thioacetamide (TAA) induced oxidative stress in male Wistar rats. Methods: In the prev...
Prescription pattern of clinicians in private health facilities in Kano, Northwestern Nigeria
Objective: To evaluate the prescription pattern of clinicians in private health care facilities in Kano, Northwestern Nigeria. Methods: One thousand prescriptions from ten private health facilities in Kano were evaluated...
Micro-emulsion based emulgel: a novel topical drug delivery system
Topical delivery systems for drugs make localized administration of the drug anywhere in the body through ophthalmic, vaginal, skin and rectal routes. Topical formulations encompass a wide variety of formulations intende...