ANTI INFLAMMATORY ACTIVITY OF ZIZIPUS MAURITIANA LAM. IN CARRAGEENAN INDUCED PAW EDEMA IN RATS AND ITS COMPARISON WITH SOME STANDARD FLAVONOIDS.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 3
Abstract
The aim of present investigation is to evaluate Anti-nflammatoryactivity of hydroalcohol extract of whole plant of Zizipus mauritiana Linn. In carrageenan induced paw edema in rats. Treatment with Zizipus mauritiana hydro alcohol extract at two different dose 200 mg/kg and 400 mg/kg and its comparison with standard drug diclofenac sodium at dose of 12.5 mg/kg and some flavonoids i.e. quercertin, kaempferol and epicatichin each at dose of 100mg/kg after induction of inflammation by carrageenan 1% solution at dose of 10 mg/kg , caused significant produce inflammation in rats hind paw It is furthermore Zizipus mauritiana at dose of 200mg/kg and 400mg/kg shows more significant result than some of standard flavonoids. Thus, whole plant of Zizipus mauritiana Lam. may have potential anti inflammatory activity.
Authors and Affiliations
Bhargava Amit*| Research Scholar, B. N. College of Pharmacy, Udaipur, Rajasthan, India, Rana A. C. | Research Scholar, B. N. College of Pharmacy, Udaipur, Rajasthan, India
Keywords
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