Anti–inflammatory, Antioxidant and Free Radical Scavenging Activities of Nyctanthes Arbor-Tristis Linn. Seed Extract Under In Vitro
Journal Title: Scholars Academic Journal of Biosciences - Year 2013, Vol 1, Issue 6
Abstract
Anti–inflammatory and Antioxidant properties of Nyctanthes arbor-tristis L. (Oleaceae) seeds extracted with Hexane, ethyl acetate and methanol revealed that ethyl acetate (Ny-El) extract showed potent effect than hexane and methanol extracts. The ethyl acetate extract exhibits 50% inhibition of anti–inflammatory activity at 7.19 ± 1.71 mg/mL. The total phenolic content of Ny-El extract was 206.81 ± 1.11 mgof catechol equivalents/g extract. Ny-El extract showed great scavenging activity on 2, 2-diphenyl-picrylhydrazyl (DPPH) (IC50 459.91±1.40 µg/mL), hydroxyl (IC50 363.32±1.58 µg/mL), nitric oxide (IC50 545.03 ± 1.69 µg/mL) andsuperoxide (IC50 338.82 ±1.72 µg/mL) radicals, as well as had high reducing power. Ny-El extract also showed a strong suppressive effect on lipid peroxidation. The metal chelating ability of Ny-El extract also showed strong inhibition effect when compared to the reference standard. Keywords: Anti–inflammatory, Nyctanthes arbor-tristis L, 2, 2-diphenyl-picrylhydrazyl, total phenolic content
Authors and Affiliations
S. Vajravijayan, A. Brabakaran, N. Thangaraju
Keywords
Related Articles
- EP ID EP377953
- DOI -
- Views 81
- Downloads 0
Screening of Ethanol extract of Combretum racemosum and Euphorbia hirta leaves for possible activity on Trypanosoma brucei brucei infected mice
Enrichment of medicinal plants with biologically active compounds which induce various chemo-therapeutic effects has made a good turn and philosophy in the science of pharmacology. In the light of the popular notion of t...
Current Trend of the Antibiogram of Salmonella Isolates at a Tertiary Care Hospital in North India
Typhoid fever continues to remain a major public health problem, especially in developing due to poor sanitation and personal hygiene. Salmonella enteric serovarstyphi and Paratyphi A&B are predominantly known to cause e...
Nebulized lidocaine an effective and safe topical anaesthetic agent to upper aero digestive tract prior to nasogastric intubation: a randomized, double-blind, placebo-controlled trial
Nasogastric intubation is a common painful procedure performed in emergency department that physicians rarely consider need for topical anaesthetic agent prior to the procedure. This study investigated the effectiveness...
Study on Awareness and Acceptance towards Computer Assisted Learning (CAL) Among Undergraduate Medical Students
Abstract: Computer Assisted Learning (CAL) is a method of acquiring knowledge using electronic media which is gaining recognition among students. This requires access to computers and considerable awareness on informatio...
Oral Lichenoid Lesion and Amalgam Restoration
Lichen planus (LP) is a chronic autoimmune disease of the skin and or mucous membranes and when the etiology is known and it involves the oral mucosa it is called oral lichen lesion. Most common site is the buccal mucosa...