Anti-inflammatory studies on a saponin albichinoside
Journal Title: Indian Journal of Pharmacy and Pharmacology - Year 2019, Vol 5, Issue 4
Abstract
Introduction Pain and inflammation are a day to day affliction for all living beings Mankind has for years been trying to relieve the agony of pain inflammation through various means with a large amount of success Still we have not been able to produce the ideal analgesic or the ideal antiinflammatory drug The objective of this study was to evaluate a saponin albichinoside with respect to its ability to relieve pain and or show antiinflammatory activityMaterials and Methods The study was conducted on rats The saponin was evaluated for its effects on acute subacute chronic and immunological inflammation by using standard antiinflammatory study protocolsResults The test substance showed significant inhibition of acute subacute and chronic inflammation produced by immunological and nonimmunological methods in rats These activities were qualitatively less as compared to indomethacin This activity was like that of nonsteroidal antiinflammatory agentsConclusion The test substance has moderate antiinflammatory activity which could be by means of inhibition of prostaglandin synthesis and the complementKeywords Saponin Antiinflammatory Animals
Authors and Affiliations
Dinesh Kansal, Naresh Naresh, Anjna Sharma
Unlicensed and off-label utilization of drugs in pediatric department at tertiary care teaching hospital: A prospective study
Background: The treatment of pediatric patients with drugs in hospitals is being impeded by a shortage in the availability of licensed drugs in an appropriate formulation. Aim of this study is to assess the extent of use...
Analysis of clinical relevance of chrono pharmacology in therapy of respiratory disorders in a tertiary care hospital- A prospective observational study
Introduction: Drugs following administration itself affect the biological rhythm or biological rhythm can affect the drug action. Administration of drugs according to biological rhythm helps in optimization and quantific...
Diagnostic use of bone biomarkers and drugs affecting bone remodelling
Bone is a dynamic organ made up of mostly collagen that provides the structure to the skeleton and calcium phosphate that gives strength and hardens the skeleton structure. Bone is constantly renewed by remodeling, a lif...
Retrospective analysis on adverse drug reactions prevalence in the female population of Tertiary Care Hospital
Introduction Adverse drug reactions seems to be a major problem in women than menObjective This study as planned to assess the incidence rate clinical manifestations and causative agents for adverse drug reactions ADRs i...
Evaluation of anxiolytic activity of rousvastatin in male albino mice
Objectives: To assess the anxiolytic activity of ROUSVASTATIN in male albino mice. To compare the anxiolytic activity of ROUSVASTATIN with standard drug as diazepam. Materials and Methods: The study was conducted in Phar...