Abstract

Objective: To investigate the antibacterial activity of Padathaali (Cyclea peltata) against three gram positive and eight gram negative bacterial strains. Methods: The fresh whole plants were collected from Kerala, India. The dry crude nonpolar and polar extract of whole plant of C. peltata i. e. Petroleum ether, hexane, chloroform, ethyl acetate, acetone, methanol and aqueous extracts of five concentrations (1, 2, 5, 10 mg/ml) were used to investigate the antibacterial activity. NCCL standards were strictly followed to perform antibacterial disc susceptibility test using disc diffusion method. Results: All the extracts showed varying degree of inhibitory potential against all the tested bacteria. Methanol extract of plant had higher inhibitory action against Staphylococcus aureus, Streptococcus haemolyticus, Klebsiella pneumonia and Proteus vulgaris. Acetone extract of plant showed maximum inhibitory action against Klebsiella pneumonia and Streptococcus haemolyticus. Conclusions: The present investigation showed the effectiveness of crude extract of this plant against tested bacterial strains. This study further suggests the use of whole plant extract in treating disease caused by tested microbial organisms.

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