Antibacterial efficacy of hydroalcoholic extract of garlic: An Invitro study
Journal Title: Medpulse International Journal of Microbiology - Year 2018, Vol 5, Issue 2
Abstract
Background: Streptococcus mutans is the predominant bacteria seen in oral diseases. A wide variety of oral hygiene products are used as disinfectants for proper maintenance of oral hygiene and to eradicate the micro-organisms, such as Cetylpyridinium chloride, Chlorhexidine, Triclosan, or antibiotics are of choice. Because of its disadvantages, there is a need for alternate, safe agent to remove the Streptococcus mutans infection. Aim: The aim of this study is to evaluate the antimicrobial activity of Hydroalcoholic extract of garlic against Streptococcus mutans. Materials and Methods: The Streptococcus mutans (ATCC35668) samples were then treated with different concentrations of Hydroalcoholic extract of garlic for different time periods. The effect of each test agent was determined by calculating the colony forming units and percentage killings of the Streptococcus mutans bacteria. The data obtained is statistically analyzed using student t test. Results: The present study shows that the Hydroalcoholic extract of garlic shows larger diameter zone of inhibition and greater inhibitory potential by MIC and MBC assays against Streptococcus mutans. Conclusion: From the study, it can be concluded that, Hydroalcoholic extract of garlic has a significant antimicrobial effect against Streptococcus mutans and can be used as oral hygiene agent for proper maintenance of oral hygiene.
Authors and Affiliations
B Nageshwar Rao, Jigni Pathan
Keywords
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