Antibacterial potential and ethnomedical relevance of Kumaun Himalayan Gymnosperms
Journal Title: The Journal of Phytopharmacology - Year 2016, Vol 5, Issue 5
Abstract
Ethnomedicinal information is one of the powerful criteria for new drugs discoveries therefore; present investigation was carried out to evaluate the ethnomedicinal and antibacterial potential of traditional Kumaun Himalayan gymnosperms. Besides, an antibacterial value index and relative antibacterial activity of studied plants have been established. Forty four plant leaves extracts in different organic solvents (methanol, ethanol, chloroform and hexane) of 11 gymnosperms (Araucaria cunninghamii, Biota orientalis, Cedrus deodara, Cephalotaxus griffithi, Cryptomeria japonica Cupressus torulosa, Ginkgo biloba, Juniperus communis, Picea smithiana, Pinus wallichiana and Taxus baccata) occurring in Kumaun Himalaya were screened for their antimicrobial activity against five pathogenic bacteria using disc diffusion method. The antibacterial activity of studied gymnospermic plant extracts against a panel of bacteria was found effective at 1000 µg/ml. The MIC and MBC values of each extract (where ZOI ≥ 15 mm) were also determined. The methanol extract of screened gymnosperms were found the most effective against all the bacteria (54% to 81%), followed by ethanol extract (45-72%), hexane extract (18-27%), while in chloroform extract it ranged 9-27% only. The extracts of G. biloba exhibited superior Relative Antibacterial Activity (RAA, 20%), followed by A. cunninghamii and P. wallichiana (12% RAA, each). The lowest RAA value was observed for C. torulosa (1%). All data were also analyzed for determination of an Antibacterial Value Index (ABVI) for each studied species of gymnosperm. G. biloba had maximum ABVI i.e. 90 % followed by A. cunninghamii and P. wallichiana (ABVI, 55% each). C. torulosa showed the least ABVI and RAA i.e. 5% and 11%, respectively. The present work fully highlighted the utility of traditionally known 11 gymnosperms of Kumaun Himalaya for their antibacterial activities against pathogenic bacteria.
Authors and Affiliations
Savita Joshi, S. C. Sati, Parikshit Kumar
Keywords
Related Articles
- EP ID EP49698
- DOI -
- Views 189
- Downloads 0
Ethnomedicinal, Antimicrobial and Pharmacological aspects of Malva parviflora Linn.: A review
Malva parviflora Linn. has shown its pharmacological potential in different ailments. Leaves are used in the management of wounds and swelling. A lotion made from the leaves is used to treat bruises and broken limbs. T...
Endothelium-dependent and independent vasorelaxant effect of Terminalia superba (Combretaceae) on rat aorta
Terminalia superba (Combretaceae) is a plant which is used in Cameroon for the treatment of many diseases including arterial hypertension. The vasorelaxant effect of the aqueous stem bark extract of T. superba was eval...
Effect of ethanolic extract of Reissantia indica on the human breast cancer cell line (MCF-7)
Reissantia indica belongs to the family Celastraceae, is a native shrub to Maharashtra and Bengal, India. Its distinct plant parts are said to possess different activities, natives of Maharashtra and Bengal are using th...
Role of Dhoopan Karma and Gauradya Ghrita in the management of Dushta Vrana (infected wound)
Ayurveda is that which deals with good, bad, happy and unhappy life, its promoters and non-promoters, measurement and nature. Shalya Tantra is a specialized branch of Ayurveda in which Surgical, Medicinal and Parasurgi...
Anthelmintic efficacy and safety of selected medicinal plants against mixed gastrointestinal nematodes in artificially infected sheep
There has been widespread resistance to anthelmintics by pathogenic helminths to an extent where there is multi-drug resistance against all major classes of conventional anthelmintics. This world-wide phenomenon calls...