ANTIBIOGRAM OF GRAM NEGATIVE UROPATHOGENS IN HOSPITALIZED PATIENTS
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2011, Vol 1, Issue 2
Abstract
Background: Urinary tract infections (UTIs) are caused by variety of microorganisms. The frequency of different bacterial isolates and their susceptibility to antibiotics may differ widely, particularly in hospitalized patients. The study of susceptibility pattern becomes obligatory for a proper selection of antibiotics. Aim: To evaluate antimicrobial susceptibility pattern of the Gram negative organisms isolated from urine cultures in hospitalized patients. Material and Methods: The present study was conducted in Yashwantrao Chavan Rural Hospital, Latur over a period of one year from June 2010 to May 2011. A total of 500 urine samples from hospitalized patients which showed significant bacteriuria were studied. Samples were inoculated on Blood agar and MacConckey agar. Further identification of organisms was done by standard Microbiological methods. Antimicrobial Susceptibility pattern was studied by Modified Kirby-Bauer’s disc diffusion method with the panel of 15 drugs as per Clinical Laboratories Standard Institute (CLSI) guidelines. Results: UTIs were found more common in females 296 (59.2%). Commonest organism found was Escherichia coli 252 (50.2%) followed by Klebsiella spp. 123 (24.6%), Pseudomonas spp. 49 (9.8%), Proteus spp. 42 (8.4%), Citrobacter spp. 27(5.4%) and Acinetobacter spp. 8 (1.6%). Majority of the strains were found sensitive to nitrofurantoin 404 (80.8%) followed by amikacin 357 (71.4%), piperacillin-tazobactam 325 (65.2%) and co-trimoxazole 254 (50.8%). Commonly prescribed fluroquinolones were found least effective for treatment of UTI. All the strains were found sensitive to imipenem. Extended spectrum beta lactamase (ESBL) was noted in 169 (67.33%) E.coli and 87 (70.73%) in Klebsiella spp. Conclusions: To discourage the indiscriminate use of antibiotics and to prevent further development of bacterial drug resistance, proper knowledge of susceptibility pattern of uropathogens in particular area is very important before prescribing empirical antibiotic therapy.
Authors and Affiliations
K Deshpande, A Pichare, N Suryawanshi, M Davane
Keywords
Related Articles
- EP ID EP134930
- DOI -
- Views 148
- Downloads 0
Phytochemical Screening and Antioxidant Activity of Tuber Extracts of Tacca pinnatifida J.R.&J.G.Forst
The Western Ghats of India are known to be a major biological hotspot that supports plant diversity and endemism. Members of the Taccaceae are famous for their use as medicinal herbs. Tacca pinnatifida J.R&J.G.Forst...
A study of congenital cardiac and extracardiac vascular anomalies in paediatric patients as detected by MDCT
Background:Clear understanding of anatomy is needed to plan effective management of congenital heart disease. MDCT provides an excellent means to detect a number of extracardiac vascular anomalies and allows accurate and...
A study of clinical, hematological and histomorphological profile of myelodysplastic syndromes
Background: Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders characterized by cytopenias, dysplasias, ineffective hematopoiesis and cytogenetic abnormalities with risk of transformation to acute myeloid...
A study on awareness and attitude of organ donation among arts college students of Thiruvannamalai district, Tamil Nadu 2017
Background: There is an increasing discrepancy between the number of patients on the waiting list for organ transplantation and the available number of donors. Evaluation of college students’ awareness and attitude is of...
Orbital cellulitis – An Unusual First Clinical Presentation in Undiagnosed Diabetic Patient
Orbital cellulitis is a common condition seen by ophthalmologists. But first time presentation of orbital cellulitis & proptosis because of undiagnosed uncontrolled diabetes and the patient being unaware of diabetes...