Antibiogram of Vulvovaginal Candidiasis amongst Pharmacy Undergraduates in a Nigerian University
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 22, Issue 12
Abstract
Objectives: To assess the knowledge, perception, incidence and the antibiogram of vulvovaginal candidiasis (VVC). Methods: Validated questionnaires were used to collect demographic information of consenting study participants and to test the participants’ level of knowledge and perception of VVC among pharmacy undergraduates. High-vaginal swab specimens were also collected for isolation of Candida species and speciation using standard yeast identification protocol and CHROMagar respectively. Results: Among the 160 participants, yeasts were detected in 43.75% and 27.50% by culture and direct microscopy respectively. Having multiple sexual partners (at least two), poor vaginal hygiene and antibiotic usage were shown to significantly increase the incidence of VVC (p<0.05). Yeasts other than Candida albicans were predominant (66.67%), especially Candida tropicalis (40.00%). Although participants’ knowledge about VVC was good (80.49%), their perception was only average (54.10%). Susceptibility test showed that the isolates were susceptible to voriconazole (84.37 ± 5.70%), fluconazole (71.54 ± 7.66%) and nystatin (65.70 ± 12.33%). The commonest isolate (Candida tropicalis) was farely susceptible to voriconazole (77.00%) and fluconazole (63.00%) but resistant to nystatin (36.00%). Conclusion: There is high prevalence of VVC despite good knowledge and average perception. Candida tropicalis was predominant in the study. Based on antibiogram, Voriconazole was the most effective drug/antibiotic and drug of choice for therapy.
Authors and Affiliations
Angus N. Oli, Chiamaka B. Ugwu, Eunice O. Osuala, Charlotte Blanche Oguejiofor, George Uchenna Eleje, Felix N. Osuala, Malachy C. Ugwu
Keywords
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- EP ID EP311986
- DOI 10.9734/JAMMR/2017/33340
- Views 85
- Downloads 0
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