ANTIBIOTIC RESISTANCE PATTERN OF BLOODSTREAM BACTERIAL ISOLATES FROM ENTERIC FEVER PATIENTS: A PROSPECTIVE CROSS-SECTIONAL STUDY
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2017, Vol 6, Issue 2
Abstract
Background:Enteric fever continues to remain a major public health problem, especially in regions of South-East Asia due to poor sanitation and personal hygiene. Bangladesh open prone to enteric fever outbreaks and is an endemic region of typhoid fever. Enteric fever caused by Salmonella typhi has not yet been adequately explored in this region. The emergence of antimicrobial resistance has complicated the treatment and management of enteric fever.Aims:To describe the pattern of bacterial isolates from the blood cultures and determine their antibiotic resistance in cases of bacteremia due to enteric fever. Methodology: This was a laboratory based prospective cross sectional study. A total of 62 isolates of Salmonella typhi&Salmonella paratyphi were found in the blood C/S report. Blood cultures were performed to isolate bacteria and susceptibility to antibiotics was assessed as per standard procedures of microbiological methods. The data was analyzed using SPSS for windows version 22.0 software.Results: Among the total isolates studied, 20% was S. typhi were found multidrug resistant (defined as resistance to ampicillin, chloramphenicol and cotrimoxazole). There was a decrease in the susceptibility to ciprofloxacin and azithromycin. Ceftriaxone and cefixime showed 100 % sensitivity. Conclusion:MDR Salmonella typhi continues to be important public health issue. Presence ciprofloxacin and azithromycin resistance is a concern and requires further study.
Authors and Affiliations
MOHAMMAD MORSHAD ALAM
Keywords
Related Articles
- EP ID EP417390
- DOI -
- Views 142
- Downloads 0
RETARDATION OF PROGRESSION OF CHRONIC KIDNEY DISEASE THROUGH PHARMACOLOGICAL INTERVENTIONS
Objective: Chronic Kidney Disease (CKD) patients have multiple co-morbidities and complications, and are prescribed with large number of medications. Studies on therapeutic strategies to slow the chronic kidney disease p...
PHARMACEUTICO THERAPEUTICS OF SULPHUR (GANDHAKA) AN AYURVEDIC REVIEW
The term Sulfur or Sulphur derived From the Sanskrit word "Shulvari"(Shulva + Ari) meaning enemy of shulva or copper metal(Anti-copper). Sulphur occurs free in abundant quantities and hence was probably known to ancient...
Immunopharmacological activity of medicinal plants against Aristolochia bracteolate and Phallus impudicus
Introduction: Immunological attempt was made to determine the potential of sevenimportant medicinally plants viz., Ficus benghalensis, Mangifera indica, Adhatoda vasica, Syzygium cumini, Terminalia arjuna, Ficus religios...
EVALUATION OF HEPATOPROTECTIVE ACTIVITY AND HISTOPATHOLOGICAL CHANGES IN LIVER OF ALBINO RATS TO FIND OUT THE EFFECT OF EXTRACT OF Sechium edule ROOTS AGAINST PARACETAMOL INDUCED HEPATIC DAMAGES
The present study was conducted to evaluate the hepatoprotective activity of Ethanolic extract of Sechium edule against paracetamol induced liver damage in rats. The Ethanolic extract of Sechium edule (300mg/kg & 600mg/k...
Assessment of Knowledge, Attitude, and Practice of First Aid, and associated factors, among Kindergarten Teachers
Background: Injuries are very common now a day and can occur at any point of time in a day to day life. Among them, injuries in school children rank a major part. The objective of this research to evaluate knowledge, att...