ANTIBIOTICS USED AS ANTI-INFLAMMATORY AND IMMUNOMODULATORY AGENTS IN DERMATOLOGICAL DISORDERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 34
Abstract
BACKGROUND Antibiotics are the drugs used for killing or inhibiting growth and multiplication of infectious organisms. Antibiotics are commonly prescribed for treatment of infections. However, antibiotics have immunomodulatory and anti-inflammatory properties and can be used for various non-infectious dermatoses. Dermatologists routinely prescribe antibiotics in treatment of various non-infectious disorders. Tetracyclines can be used in Bullous pemphigoid, Acne vulgaris, Rosacea, Hidradenitis suppurativa, Pyoderma gangrenosum, Linear IgA disease and Dermatitis herpetiformis.1 This clinical study will review anti-inflammatory and immunomodulatory effects of Tetracyclines used in 15 patients of bullous pemphigoid (04), acne vulgaris (06), pyoderma gangrenosum (03) and rosacea (02) along with vitamin B3 (niacinamide). These drugs can be used as steroid sparing agents when other comorbidities are present in elderly patients.
Authors and Affiliations
S. Showkath Ali, T. Praveena, M. Madhavi Lata, Mastan Saheb
TO COMPARE THE EFFICACY OF INTRAVENOUS MIDAZOLAM VERSUS CLONIDINE AS PREMEDICANTS ON BISPECTRAL INDEX-GUIDED PROPOFOL INDUCTION OF ANAESTHESIA IN GENERAL SURGERY
BACKGROUND Laryngoscopy and endotracheal intubation are potent stimuli that can induce increased sympathetic activity leading to tachycardia, hypertension and dysrhythmias. Various drugs and methods have been tried to ob...
TO STUDY THE EFFECT OF IRON DEFICIENCY ANAEMIA ON HbA1C IN NON-DIABETIC
BACKGROUND The most common form of anaemia plaguing our country is Iron deficiency anaemia. The extent of diabetic control is measured by HbA1c, which is the average blood glucose level of the patient over the past 3 mon...
CLINICAL STUDY AND MANAGEMENT OF VENTRAL HERNIAS IN ADULTS
BACKGROUND Hernia is defined as abnormal protrusion of viscous through a normal or abnormal weakness in the wall of its containing cavity. Ventral hernias are the second most common type of hernias accounting for 21% to...
CARCINOEMBRYONIC ANTIGEN LEVELS AMONG STROKE PATIENTS
BACKGROUND CEA (carcinoembryonic antigen) is mainly associated with malignant conditions, but there is a modest increase in non-malignant conditions such as aging, and atherosclerosis and this study is to find correlatio...
SPECTRUM OF BENIGN BREAST DISEASES ON A REMOTE INDIAN ISLAND
BACKGROUND Lump in the breast has assumed increasing importance in recent years because of the public awareness of breast cancer. Benign lesions of breast are the most common lesions and constitute a heterogeneous group...