ANTIMALARIAL ACTIVITY OF SWARTZIA MADAGASCARIENSIS DESV. (LEGUMINOSAE), COMBRETUM GLUTINOSUM GUILL. & PERR. (COMBRETACEAE) AND TINOSPORA BAKIS MIERS. (MENISPERMACEAE), BURKINA FASO MEDICINAL PLANTS.
Journal Title: African Journal of Traditional, Complementary and Alternative Medicines - Year 2006, Vol 3, Issue 1
Abstract
Swartzia madagascariensis, Combretum glutinosum and Tinospora bakis are three plants of the folk medicine used by healers in Burkina Faso for the treatment of malaria. A scientific validation of this utilization was not previously made. Aqueous, methanol, hydromethanol extracts from the roots bark of S. madagascariensis, methanol and hydromethanol extracts from the leaves of C. glutinosum and aqueous and alkaloidal extracts from the roots of T. bakis were also made and their antimalarial activity was screened against Plasmodium falciparum chloroquine-resistant strain W2 in vitro. The screening showed that the methanol and hydromethanol extracts of Swartzia madagascariensis, hydromethanol extracts of Combretum glutinosum and alkaloidal extracts of Tinospora bakis were active (5µg/ml < IC50 < 50 µg/ml).
Authors and Affiliations
Y. Ouattara, S. Sanon, V. Mahiou, N. Azas, L. Sawadogo
Keywords
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