Antimicrobial Activity of Cyminum cuminum Against Biofilm E. coli
Journal Title: International Research Journal of Applied and Basic Sciences - Year 2013, Vol 5, Issue 10
Abstract
Uropathogenic organisms have evolved numerous defense mechanisms against antimicrobial agents, hence resistance to old and newly available drugs are increasing at an unprecedented level. The events of antibiotic resistance have lead for screening of several medicinal plants for their potential antimicrobial activity. The aim of this study was to evaluate the antimicrobial efficacy of Cyminum cuminum against biofilm Escherichia coli. Cuminis an annual plantof the Umbelliferae family. Cumin is an important medical herb in Asia and has antioxidant, anticholesterol and antimicrobial properties. ethanol extracts of seed of Cyminum cuminum were tested for antimicrobial activity in vitro by the microdilution method. Ethanol extract of seed exhibited antimicrobial activity against biofilm Escherichia coli. It can be concluded that Cyminum cuminumcan be used to discover natural products that may serve as lead for the development of new pharmaceuticals, addressing the major therapeutic needs especially for biofilm E.coli.
Authors and Affiliations
Zakaria Bameri1| Infectious Diseases and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.Department of Biology, Faculty of Science, Islamic Azad University,Zahedan, Iran., Negar Amini-Boroujeni| Department of Biology, Faculty of Science, Islamic Azad University(Science and Resercher), Kerman, Iran., SaeideSaeidi *| Department of Biology, Faculty of Science, Islamic Azad University(Science and Resercher), Kerman, Iran.Department of Biology, Faculty of Science, Payam nor University, Zabol, Iran.email:s.saeedi12@yahoo.com, Saphora Bazi| Department of Biology, Faculty of Science, Payam nor University, Zabol, Iran.
Keywords
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