Antimicrobial Efficacy of Chlorhexidine and Licorice Mouthwashes in Children
Journal Title: Meandros Medical and Dental Journal - Year 2019, Vol 20, Issue 1
Abstract
Objective: The aim of this in vivo study is to evaluate the effectiveness of a simple herbal caries-prevention protocol for reducing salivary Streptococcus mutans levels in children. Materials and Methods: A total of 90 individuals were recruited randomly divided into three groups (n=30). Mouthwashes including chlorhexidine (CHX), licorice and saline were used as tested antimicrobial agents, and saliva samples were collected before rinsing, at the end of 5 min (T1) and 60 min (T2) following rinsing, and the differences were calculated within 5-60 min (T3). Plaques were evaluated following incubation, and counts of the growing colonies were performed in colony forming units (CFU)/mL. Decreases in CFU were calculated in ratio for statistical analysis. Data were analyzed with Kruskal-Wallis, Mann-Whitney U, Friedman and Wilcoxon signed rank tests by Bonferroni correction, using a 0.05 of significance level. Results: CHX caused significantly different decreases for T1 and T2 (p<0.05), but, there were no significant differences between CHX and licorice for T3 (p>0.05). Conclusion: Licorice might be a useful agent for dental procedures and further studies are needed to learn more about the dose of licorice, the ratio of glycyrrhizin and the duration of dental therapy.
Authors and Affiliations
Fatih Öznurhan, Burak Buldur, Özgül Cartı, Uğur Tutar, Cem Çelik, Ceylan Hepokur
Keywords
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- EP ID EP48906
- DOI 10.4274/meandros.galenos.2018.79663
- Views 363
- Downloads 0
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