Antimicrobial Resistance Pattern and Frequency of Multiple-Drug Resistant Enterobacter Spp. at A Tertiary Care Hospital in Southwest of Iran
Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2017, Vol 6, Issue 2
Abstract
Background: Strains belonging to Enterobacter genus are important opportunistic nosocomial pathogens. Resistance to broad-spectrum antibiotics often complicates the treatment of Enterobacter infections. Aim and Objectives: The present study was aimed to determine the frequency and antibiotic resistance patterns of Enterobacter spp. obtained from a specialized Women's and Children's hospital. Material and Methods: This retrospective study was conducted during September 2015 to July 2016 in Shiraz, Iran. Enterobacter isolates were obtained from various clinical specimens and were identified using standard microbiological procedure. Antimicrobial susceptibility patterns were determined in accordance with CLSI recommendation. Results: Out of 61 Enterobacter spp., majority of isolates were obtained from blood 11 (18%) and followed by urine and eye specimens (11.5%). Antibiotic susceptibility revealed that all isolates were resistance to amikacin, and mostly resistance to cefotaxim and gentamycin with 90.2% and 75.4%, respectively. The highest sensitivity was toward polymyxin B 96.7%, co-trimoxazole 65.6% and imipenem 57.4%. Overall, the rate of Multiple Drug Resistant (MDR) isolates were 91.8% (n=56). Of MDR isolates, 39.2% of isolates were resistance to at least 3 antibiotics. Conclusion: Despite the significant role of MDR isolates in occurrence of infections, several locally available antibiotics still can have promising effects on outcome of Enterobacter infections in pregnant women and neonates.
Authors and Affiliations
Yalda Malekzadegan, Mahtab Hadadi, Hadi Sedigh Ebrahim-Saraie, Hamid Heidari, Mohammad Motamedifar
Keywords
Related Articles
- EP ID EP227507
- DOI -
- Views 101
- Downloads 0
Papillary Microcarcinoma in Multinodular Goiter with Lymphocytic Thyroiditis
Multi nodular goitre (MNG) is one of the common presentations of various thyroid diseases. Hitherto issue is whether MNG is significantly associated with malignancy. Various studies have reported a 7 to 17% incidence...
Degloving Injury of Ascending Colon Following Blunt Abdominal Trauma
Degloving injury to the colon caused by blunt abdominal trauma is an extremely rare injury. To our knowledge, this is the first reported case of degloving injury to the ascending colon in the literature which further acc...
Idiopathic Retroperitoneal Fibrosis with Bilateral Varicocele – A Rare Presentation of Very Rare Clinical Entity
Retroperitoneal fibrosis is a very rare inflammatory disease leading to extensive fibrosis throughout the retroperitoneum. The majority of cases are idiopathic in which the exact cause is not known. The clinical presenta...
Patience Pays Off: A Case of Self Exfoliation of Large Parotid Sialolith
Sialolithiasis is one of the common diseases affecting the salivary glands. The submandibular gland is the most commonly affected gland among the three major salivary glands. The incidence of parotid sialolith is rare an...
Fetal Medicine