Antimicrobial utilization study in the department of surgery in a tertiary care teaching rural hospital
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2019, Vol 8, Issue 1
Abstract
Introduction The purpose of surgical prophylaxis is to reduce the incidence of surgical site infection (SSI) with minimal alteration of normal microbial flora of the host and minimal adverse effects. Methodology In present study 200 patients have been included from Surgery Department over six month period. Result The common antimicrobials prescribed were third-generation cephalosporins (90.5%), followed by aminoglycosides (58%). Commonly prescribed individual antimicrobial agents were amikacin (58%), ceftriaxone (45%), metronidazole (40%) and cefixime (13%) and the common combination used were amoxicillin + clavulinic acid (21%), cefoperazone + sulbactam (18%), ofloxacin + ornidazole (16%), ceftriaxone + sulbactam (12.5%) and piperacillin + tazobactam (11%). Conclusion Cephalosporins and aminoglycosides were the most commonly prescribed prophylactic antimicrobial agents. Prophylactic antimicrobial agents should be prescribed appropriately using standard guideline.
Authors and Affiliations
Rushika S Modi
Keywords
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