Antral Follicle Count in Normal (Fertility-Proven) and Infertile Indian Women
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 1
Abstract
Antral follicle count (AFC) has been labeled as the most accurate biomarker to assess female fecundity. Unfortunately, no baseline Indian data exists, and we continue using surrogate values from the Western literature (inferred from studies on women, grossly different than Indian women in morphology and genetic makeup). Aims: To establish the role of AFC as a function of ovarian reserve in fertility-proven and in subfertile Indian women. To establish baseline cut-off AFC values for Indian women. Materials and Methods: Thirty patients undergoing workup for infertility were included and compared to equal number of controls (women with proven fertility). The basal ovarian volume and AFC were measured by endovaginal. USG the relevant clinical data and hormonal assays were charted for every patient. Statistical Analysis Used: SPSS platform was used to perform the Student’s t-test and Mann-Whitney U-test for intergroup comparisons. Correlations were determined by Pearson’s ranked correlation coefficient. Results: Regression analysis revealed the highest correlation of AFC and age in fertile and infertile patients with difference in mean AFC of both the groups. Comparison of the data recorded for cases and controls showed no significant difference in the mean ovarian volume. Conclusions: AFC has the closest association with chronological age in normal and infertile Indian women. The same is lower in infertile women than in matched controls. Baseline and cut-off values in Indian women are lower than that mentioned in the Western literature.
Authors and Affiliations
Dr Sanjay Kumar Chowdhury
Keywords
Related Articles
- EP ID EP273380
- DOI -
- Views 103
- Downloads 0
Development and Validation of Simultaneous RP-HPLC Method for Estimation of DROTAVERINE HCl and MEFENAMIC Acid in bulk and Pharmaceutical Formulations
A simple, specific, accurate and precise RP HPLC method has been developed for the simultaneous determination of Drotaverine HCl and Mefenamic Acid from combined dosage form by reverse phase C18 column (Younglin ( S.K) G...
Primary cutaneous facial phaeohyphomycosis due to Verruconus gallopava (Ochroconus gallopava) in an immunocompetent woman from the SubHimalayas – a case report and literature review
Verruconus gallopava is a melanised environmental saprophyte. Human infections of respiratory and central nervous systems occur primarily in immunocompromised subjects. Skin and subcutaneous infections are seen when dise...
Clinico- epidemiological profile of vitiligo patients attending outpatient department of JNIMS
Background: Vitiligo is an acquired depigmenting disorder characterized by amelanotic macules resulting from loss of melanocytes. Objective: To study the clinico-epidemiological profile of vitiligo patients attending the...
Effects of Music Therapy on Anxiety, Pain & Clinical Parameters among Primigravida in a Selected Hospital, West Bengal
Background: Labour is accompanied by intense and prolonged pain. For many years researchers are trying to find a safe, effective way of reducing the pain perception without hampering the fetal outcome. Aim: To find out t...
To Assess Migraine Headache in Children: A Clinical Study
Background: Migraine is a primary headache disorder characterized by recurrent headaches. It is quite common in adults with prevalence rate of 20%. Migrainous headache is prevalent in 4% of children in the age group 7 to...