Apophysomyces elegans Caused Rhino-Orbito Mucormycosis: An Emerging Infection in Immunocompetent Individuals
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2017, Vol 7, Issue 4
Abstract
Mucormycosis is a rare necrotizing angioinvasive infection caused by fungi of the class Zygomycetes (order Mucorales). It predominantly occurs in immunocompromised/ predisposed individuals. Recent surge in its incidence in healthy individuals has emphasized the need to reconsider our age-old presumption of 'mucormycosis as a classical opportunistic infection'. Apophysomyces elegans has emerged as a pathogen causing invasive Rhino-Orbitocerebral Mucormycosis (ROCM), mostly in immunocompetent individuals. Mostly resistant to commonly used azoles and echinocandins, management of A. elegans associated ROCM solely depends on radical debridement and Amphotericin B. Recent reports of Amphotericin B resistant A. elegans strains is disturbing. Till date only 12 cases of ROCM in immunocompetent/ otherwise healthy individuals attributable to A. elegans has been reported. Our main objective is to delineate the clinical characteristics and treatment outcome of immunocompentent/ otherwise healthy individuals suffering from A. elegans caused ROCM. We also report four new cases of A. elagans caused ROCM. J Microbiol Infect Dis 2017; 7(4):207-212
Authors and Affiliations
N. Dhaneshwor Singh, Nishi Sharma, Lobzang Dawa, Shalini Malhotra
Keywords
Related Articles
- EP ID EP413790
- DOI -
- Views 111
- Downloads 0
First time isolation of Pseudomonas argentinensis from human skin infection
This reported the first isolation of Pseudomonas argentinensis from a human nfection, since the discovery of P. ar gentinensisin 2005. A Palestinian 63-year male practicing gardening on sunny days with exposed arms and l...
Akut Hepatit A’ya Bağlı Gelişen Jeneralize Prüritus: Olgu Sunumu
A-Hepatiti Hepatit A virüsünün neden olduğu bir akut karaciğer infeksiyon hastalığıdır. Pek çok vakada ya çok az semptom vardır ya da hiç yoktur. Olgumuzda, 19 yaşlarında bir kadın hasta aşırı halsizlik, sarılık ve diffü...
Non-typhoidal Salmonella isolates from livestock and food samples, Kolkata, India
ABSTRACT Objective: Non-typhoidal Salmonella (NTS) is a major foodborne pathogen in both developed and developing countries. The study was undertaken to determine the prevalence, serotype distribution and antimicrobial r...
Emergence of Pan-drug resistance amongst gram negative bacteria! The First case series from India
Objective: Increasing prevalence of carbapenem resistant Gram negative bacteria is a serious clinical and public health challenge. Bacteria resistant to all available antibiotics (Pan Drug Resistance) herald the onset of...
Laktozu fermente eden Salmonella paratyphi A: Bir vaka sunumu
Salmonella genusunda 2500’den fazla antijenik tipleri bulunmaktadır. Salmonella typhi ve Salmonella paratyphi A, B ve C tifo etkenidirler. Karakteristik olarak bu dört tür de laktozu fermente etmezler. Burada, 12 günlük...