APPLICATION OF CHITOSAN IN THE FORMULATION OF DERMATOLOGICAL HYDROGELS PREPARED ON THE BASIS OF MACROMOLECULAR COMPOUNDS
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2018, Vol 0, Issue
Abstract
The effect of chitosan concentration on the properties of dermatological preparations prepared with 2% methylcellulose and 10% polyvinylpyrrolidone was studied. As the levels of chitosan, propylene glycol-1,2 and glycerol increased, the hardness, consistency and cohesiveness of the hydrophilic gels increased, while the dissipation capacity decreased. Gels based on methylcellulose and chitosan, compared to formulations containing polyvinylpyrrolidone, have a higher rate of loss of volatile compounds, higher pH values for 1,2-propylene glycol formulation and higher texture parameters. The tested hydrogels have good rheological properties, allowing extrusion from the tube and spreading on the skin.
Authors and Affiliations
Maria Szcześniak, Bożena Grimling, Jan Meler
Keywords
Related Articles
- EP ID EP537304
- DOI 10.15259/PCACD.23.18
- Views 79
- Downloads 0
ATORVASTATIN ADSORPTION STUDIES ON CHITOSANS IN AN in vitro PHARMACEUTICAL MODEL
During the pharmacological therapy of specific diseases, drugs are used which, with other preparations or foods, can create connections, in many cases changing or even blocking their action. On the other hand, the use of...
INHIBITION OF CHITIN DEACETYLASE BY ACETIC ACID PRELIMINARY INVESTIGATION
The current paper reports on a preliminary investigation of the mechanism of inhibition of chitin deacetylase isolated from Absidia orchidis vel coerulea by the acetic acid released during the deacetylation process. It i...
FORMATION AND CHARACTERIZATION OF SUCCINOYL CHITOSAN PARTICLES LOADED WITH WARNERIN
This study aims to obtain nanoparticles based on succinoyl chitosan loaded with Warnerin (War-SCNPs), low molecular weight cationic peptide. The nanoparticles of succinoyl chitosan (SCNPs) were prepared by salt coacervat...
PREPARATION AND CHARACTERIZATION OF CRYOGELS BASED ON PECTIN AND CHITOSAN
Novel cryogels based on pectin and chitosan were obtained by a cryotropic gelation method. Percentage of chitosan in the cryogels was estimated by elemental analysis. The obtained values were from 3.50 to 15.03 % for App...
APPLICATION OF CHITOSAN IN THE FORMULATION OF METHYL CELLULOSE-BASED HYDROGELS
The aim of this work was to study the properties of methylcellulose hydrogels with supplements containing chitosan and 1% hydrocortisone. Depending on the composition of the substrate, gels are characterised by a variety...