Statistical optimization of a novel excipient (CMEC) based gastro retentive floating tablets of propranolol HCl and it's in vivo buoyancy characterization in fed and fasted states. From the results, it was concluded that gastric residence time of the floating tablets were enhanced at fed stage but not in fasted state.healthy human volunteers

The objective of the present investigation is to formulate gastro retentive floating drug delivery systems (GRFDDS) of propranolol HCl by central composite design and to study the effect of formulation variables on flo...

Methamphetamin abuse a new concern in Iran

The major role of toxicology societies in global collaborations - a call to action

The science of toxicology in all of its various aspects is, of necessity, a global one. The production and release of potentially toxic chemicals is increasing in many parts of the world. While this can cause local envir...

Comment on " An update on toxicology of aluminum phosphide "

I read with interest the recent published article by Dr Moghadamnia titled "An update on toxicology of aluminum phosphide". Since aluminum phosphide (AlP) poisoning is an important medical concern in Iran, I have had the...

Cost-effectiveness of adding-on new antiepileptic drugs to conventional regimens in controlling intractable seizures in children

Background and purpose of the study Intractable seizures are a subgroup of epileptic disorders challenging the physicians' skills to become controlled. Showing resistance towards common pharmacotherapy, they demand newer...