“APPRAISAL OF ANTIBIOTICS USE IN A SECONDARY CARE HOSPITAL IN SOUTH INDIA.
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2017, Vol 7, Issue
Abstract
Abstract The emergence of antibiotic resistant bacteria is major problem throughout the world and rational use of antibiotics is therefore very important. Good infection control practice is a critical component for success of such programme. This six months prospective observational study was designed to evaluate the appropriateness of antibiotic use in a secondary care referral hospital of South India. The data of all in patients (n=100) were collected by obtaining a proper consent. Maximum of 52.78% patients had culture sensitivity test being done, which may taken as a indication for being rational. The results revealed that the purpose of antibiotics prescribed was for prophylaxis (15%), empirically (37%) and therapeutically 48%. In the study population (n=49) (patients had shown a positive culture study reports for urine, sputum, pus and blood samples), totally 110 antibiotics were prescribed, 71.88% on dual therapy and 28.12% were on three antibiotics and the mean number of antibiotics prescribed was 2.28. In the overall population, 61.65% were administrated intravenously and 39.35% of oral antibiotics The major organisms identified were E.coli (28.90%) and amikacin had shown the highest sensitivity in E.coli (86.4%). Totally 31 drugs of antibacterials were listed in National List of Essential Medicine. Out of 31, 15 antibacterials were prescribed instudy population.
Authors and Affiliations
Dr. Karthik Muthusamy1, Dr. R. Venkateswara Rao2, N. V. Rama Rao2, Prof. Nadendla. Rama Rao2.
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