Aprepitant for treatment of refractory vomiting in a case of brain abscess
Journal Title: IJAR-Indian Journal of Applied Research - Year 2017, Vol 7, Issue 4
Abstract
We report a case of brain abscess whose intractable nausea and vomiting improved significantly with aprepitant, a neurokinin (NK) receptor antagonist currently licensed only for prevention of chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV). The nausea and vomiting which was refractory to most of the antiemetics showed dramatic response to three doses of aprepitant. This novel NK receptor antagonist, aprepitant has a potential role not only for prevention but also for treatment of refractory vomiting in oncology and non oncology setting.
Authors and Affiliations
Sqn Ldr Navjyot Kaur, Maj Pritam Purohit
Keywords
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