Arrhythmias in adult patients after total correction of tetralogy of Fallot (RCD code: V-2B.0)
Journal Title: Journal of Rare Cardiovascular Diseases - Year 2013, Vol 1, Issue 4
Abstract
Improvement of the long‑term survival of patients with Tetralogy of Fallot has been observed in the last few years. Among the late complication arrhythmias are detected most frequently. The aim of this study was to estimate the frequency of atrial and ventricular arrhythmias in the group of 53 adult tetralogy patients. Mean age was 29 years, 21 patients (39,6%) were women. In 4 cases (7,5%) palliative pulmonary‑systemic shunt was performed. Average age of total surgical correction was 6,55 years. Significant ventricular arrhythmias were present in 15 patients (28,3%). 9 (17%) had relevant atrial arrhythmias. Patients with atrial arrhythmia were older (35,4 vs 27,7 years). Older were also patients with ventricular arrhythmias (34,7 vs 26,4 years). Group with atrial arrhythmia used more digoxin (p=0,002) and diuretics (p = 0,021). 3 patients on oral anticoagulants had atrial flutter. Similar data was collected in group with ventricular arrhythmias (diuretics p = 0,0053). There was a high incidence of coexisting ventricular and atrial arrhythmias (p=0,0057). Left ventricular enlargement was present in patients with atrial (p = 0,002) and ventricular (p = 0,027) arrhythmias. Right atrium area and left atrium diameter were greater in group with supraventricular arrhythmias (31,6 vs 21,6 cm2 and 40,4 vs 34,3 mm; respectively). Ventricular arrhythmias were associated with greater right (27,8 vs 21,0 cm2) and left atrium areas (18,5 vs 15,1 cm2). Younger age at the time of corrective surgery is associated with lower frequency of arrhythmias in adults. Arrhythmias however remain one of the most significant problems in this group of patients. Close observation in centers specialized in Grown‑Up Congenital Heart Defects and management of symptoms seems to be the best option in long‑term follow‑up. JRCD 2013; 1 (4): 10–15
Authors and Affiliations
Agnieszka Żygadło, Lidia Tomkiewicz- Pająk, Natalia Dłużniewska, Maria Olszowska, Piotr Podolec
Keywords
Related Articles
- EP ID EP248133
- DOI 10.20418/jrcd.vol1no4.64
- Views 153
- Downloads 0
The role of biomarkers as an alternative and completion of the diagnostic and therapeutic pathway in patients with aortic stenosis (RCD code: VIII)
Aortic stenosis (AS) is the most frequent type of valvular heart disease. Clinically, it presents as calcific and congenital AS. Calcific AS is often age dependent and affects 2–7% of people over 65 years of age. Many cl...
Facilitating recognition and grouping the expertise in the main fields of rare cardiovascular diseases
Dear Friends and Colleagues, Dear Readers,We are pleased to deliver at your hands the second issue of your quarterly Journal of Rare Cardiovascular Diseases. The feedback we have received, after launching the Journal in...
Biventricular cardiomyopathy improvement by shifting therapy from agalsidase alfa to agalsidase beta in Anderson‐Fabry Disease
Treatment of Fabry disease has improved since the introduction of enzyme replacement therapy (ERT). Two preparations of the recom‐ binant enzyme α‐galactosidase A are available: agalsidase alfa and agalsidase beta. We ai...
A 34‐year‐old man with non‐obstructive apical hypertrophic cardiomyopathy (RCD code: III‐2A.1)
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium that is defined by the presence of regional (more frequent) or global myocardial hypertrophy, which usually results in functional cardiac impairmen...
Pregnancy in pulmonary arterial hypertension (RCD code: VII‑II‑1)
Pulmonary arterial hypertension (PAH) is a progressive disease leading to right ventricular failure and death, if not treated adequately. Pregnancy in women with PAH is associated with significantly high mortality, thus...