Arterial hypertension in adrenal incidentalomas
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 11
Abstract
Arterial hypertension is a life threatening sign of overt Cushing syndrome. In the incidentally found adrenal tumours (adrenal incidentalomas – AI) subclinical adrenal hyperfunction sometimes has been observed; hormonally dependent arterial hypertension may have an adrenocortical origin (subclinical hypercortisolism, aldosterononism or – rarely – congenital adrenal hyperplasia, t. II) or chromaffin cell origin (pheochromocytoma). The most frequent mechanism of arterial hypertension is subclinical excess of cortisol. This study aimed at evaluation of frequency of arterial hypertension and its aetiology in a group of 2430 patients with AI (90% with probably benign tumours and 7% with adrenocortical cancer). Arterial hypertension has been noted in 1003 patients (41%), however in about 10% not exceeding 140/95 mmHg. The material has been analyzed basing on oncological and endocrinological criteria. In probably benign tumours arterial hypertension was present in 42%, while in adrenocortical cancer – in 39%. Hormonal analysis revealed pre-Cushing’s syndrome in 136 patients (5.6%), hyperaldosteronism in 34 ones (1.4%) and pheochromocytoma in 65 patients (2.7%) Arterial hypertension was found in almost all patients with subclinical Cushing’s syndrome, all patients with hyperaldosteronism and in about 3/4 of the patients with chromaffin tumours. In comparison with obesity and diabetes mellitus arterial hypertension was the most frequent component of the metabolic syndrome.
Authors and Affiliations
Anna Kasperlik-Załuska, Jadwiga Słowińska-Srzednicka, Elżbieta Rosłonowska, Wojciech Jeske, Maciej Otto, Andrzej Cichocki
Keywords
Related Articles
- EP ID EP54324
- DOI -
- Views 147
- Downloads 0
Emotional state versus quality of life of patients with chronic neuropathic pain
Introduction. Chronic neuropathic pain is a serious in medicine, primarily due to a significant degree of intensity of pain and resistance to traditional treatment, which affects the functioning of the physical, psycholo...
The effect of hyperaldosteronism on the cardiovascular system
Hyperaldosteronism causes arterial hypertension, fibrosis and hypertrophy of blood vessel muscles and myocardium, is proinflamatory and prothrombothic state and decreases endothelium function.<br>Patients w...
Demodex folliculorum in rosacea based on a modified standardized skin surface biopsy
Introduction. Rosacea is a chronic disease characterized by (depending on the subtype) facial prolonged erythema, sometimes pustules or nodules. Rosacea affects all ages and sex with four subtypes. Pathophysiology aims t...
Renal artery stenosis of the transplanted kidney as a cause of posttransplant arterial hypertensionRenal artery stenosis of the transplanted kidney as a cause of posttransplant arterial hypertension
Hypertension after kidney transplantation is a very common disease and its etiology is usually complex. One of the causes of hypertension after kidney transplantation is transplanted renal artery stenosis (TRAS). The cli...
Arterial hypertension in adrenal incidentalomas
Arterial hypertension is a life threatening sign of overt Cushing syndrome. In the incidentally found adrenal tumours (adrenal incidentalomas – AI) subclinical adrenal hyperfunction sometimes has been obser...