ASSESSMENT OF ANTIOXIDANT, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF ETHANOL EXTRACT OF LEAVES OF CROTALARIA PALLIDA (AITON)
Journal Title: International Journal of Pharmacognosy - Year 2014, Vol 1, Issue 7
Abstract
The ethanol leaves extract of Crotalaria pallida (Aiton) was evaluated to investigate the Phytochemical nature and some selected pharmacological activities. The plant extract indicated the presence of combined reducing sugar, tannins, flavonoids, glycosides, alkaloids and steroids. The extract showed free radical scavenging activity with an IC50 value of 37.60 µg/ml, and standard ascorbic acid showed IC50 value of 16.95µg/ml. The total phenolics content (TPC) was found to be 14 ± 0.015 mg GAE/g of dried plant extract. Total flavonoids content was found to be 20.42 ± 0.001 mg QE / 100 g of dry extract. The extract showed mild antibacterial activity against the bacterial strains Vibrio cholera, Shigella flexneri, Shigella dysenteriae, in comparison with standard drug kanamycin (30 µg/disc). In the anthelmintic test, the extract showed a dose-dependent decrease in paralysis time and death time of worm Paramphistomum cervi (trematoda) when compared with standard albendazole. These results espouse the traditional use of the leaves of this plant.
Authors and Affiliations
M. H. Alam et al.
Keywords
Related Articles
- EP ID EP555684
- DOI -
- Views 355
- Downloads 0
PHYTOCHEMICAL SCREENING AND FRACTIONATION OF MOMORDICA CHARANTIA LINN. FRUIT TO SHOW ANTIHYPERGLYCAEMIC ACTIVITY
Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available...
WOUND HEALING ACTIVITY OF SOME MEDICINAL PLANTS: REVIEW
The traditional Indian medicine - Ayurveda, describes various herbs, fats, oils and minerals with anti-aging as well as wound healing properties. Wounds are the result of injuries to the skin that disrupt the soft tissue...
GASTRO PROTECTIVE EFFECTS OF USNEA LONGISSIMA METABOLITES ON PROBIOTIC LACTOBACILLUS CASEI
Protective effect of probiotic combination of Usnic acid and Lactobacillus casei in experimentally induced ulcer in rats was investigated. Rats inward Usnic acid (100 mg/kg), L. casei (10-8 con.), Usnic acid (100 mg/kg)...
PHYTOCHEMICAL SCREENING OF AQUEOUS AND ETHANOL EXTRACTS OF SOME MEDICINAL PLANTS AND IN -VITRO STUDY OF INHIBITION OF α- AMYLASE
In the present study we screened four medicinal plants for the α-amylase inhibitory activity of each extracts phytochemicals, and it was determined based on the colorimetric assay using acarbose as a reference compound....
PHARMACOGNOSTIC AND PRELIMINARY PHYTOCHEMICAL SCREENING OF LEAVES OF CYNODON DACTYLON PERSOON
Many plants used as traditional medicine. Pharmacognostic studies of crude drug play a very important role in the identification of the purity and quality of crude drugs. The present study deals with the pharmacognostic,...