ASSESSMENT OF ANTIOXIDANT, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF ETHANOL EXTRACT OF LEAVES OF CROTALARIA PALLIDA (AITON)
Journal Title: International Journal of Pharmacognosy - Year 2014, Vol 1, Issue 7
Abstract
The ethanol leaves extract of Crotalaria pallida (Aiton) was evaluated to investigate the Phytochemical nature and some selected pharmacological activities. The plant extract indicated the presence of combined reducing sugar, tannins, flavonoids, glycosides, alkaloids and steroids. The extract showed free radical scavenging activity with an IC50 value of 37.60 µg/ml, and standard ascorbic acid showed IC50 value of 16.95µg/ml. The total phenolics content (TPC) was found to be 14 ± 0.015 mg GAE/g of dried plant extract. Total flavonoids content was found to be 20.42 ± 0.001 mg QE / 100 g of dry extract. The extract showed mild antibacterial activity against the bacterial strains Vibrio cholera, Shigella flexneri, Shigella dysenteriae, in comparison with standard drug kanamycin (30 µg/disc). In the anthelmintic test, the extract showed a dose-dependent decrease in paralysis time and death time of worm Paramphistomum cervi (trematoda) when compared with standard albendazole. These results espouse the traditional use of the leaves of this plant.
Authors and Affiliations
M. H. Alam et al.
Keywords
Related Articles
- EP ID EP555684
- DOI -
- Views 355
- Downloads 0
ANTIINFLAMMATORY ACTIVITY OF FLOWER EXTRACT OF BUTEA MONOSPERMA
Butea monosperma (Family: Fabaceae). This is a moderate sized deciduous tree which is widely distributed throughout India, Burma and Ceylon, popularly known as 'dhak' or 'palas,' commonly known as ‘Flame of the forest’....
PHYSICOCHEMICAL AND PHYTOCHEMICAL EVALUATION OF CHLOROPHYTUM BORVILIANUM AND SAPINDUS MUKORROSSAI
The study is aimed at development of physico-chemical parameters and to investigate the active principle present in Chlorophytum borvilianum and Sapindus mukorrossai. The present work embodies the investigations carried...
ANTIMICROBIAL SOCKS FORMULATION WITH SILVER NITRATE
Antiseptics and Disinfectants are extensively used in the health care industry and also equally in personal hygiene. Among the chemicals, silver has long been known to have antimicrobial activity. Development of new, eff...
EVALUTION OF ANTHELMINTIC ACTIVITY OF RICINUS COMMUNIS LINN. LEAVES
Aqueous and ethanol ethyl actatate chloroform methanol extracts from the leaves of Ricinus communis were investigated for their anthelmintic activity against Pheretima posthuma and three concentrations (50, 75 and 100mg/...
COMPARATIVE STANDARDIZATION STUDY OF THREE TRIPHALA CHURNA FORMULATION
In the few decades, there has been exponentially growth in the field of herbal medicines. Most of the traditional system of medicine is effective but they lack standardization. So there is a need to develop a standardiza...