ASSESSMENT OF CASES OF ACUTE VIRAL HEPATITIS IN CORRELATION WITH LIVER PROFILE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 14
Abstract
BACKGROUND Typical symptoms of acute hepatitis are fatigue, anorexia, nausea, and vomiting. Very high aminotransferase values (>1000 U/L) and hyper bilirubinaemia are often observed. Severe cases of acute hepatitis may progress rapidly to acute liver failure, marked by poor hepatic synthetic function. This is often defined as a prothrombin time (PT) of 16 seconds or an international normalized ratio (INR) of 1.5 in the absence of previous liver disease. We wanted to assess correlation of various types of acute viral hepatitis with liver function tests. METHODS The present study was a case control analytical study, conducted among 30 probable cases of acute viral hepatitis, admitted under department of general medicine, KIMS, Karad, during the period of October 2015 to March 2017. RESULTS In this study, the majority of the cases presented with nausea/vomiting and dark yellow urine 86.6% (26) cases, followed by anorexia and icterus 83.3% (25) cases, abdomen pain was in 60% (18) cases, fever was in 53.3% (16) cases, hepatomegaly was in 36.6% (11) cases and pruritus was in 23.3.% cases. There was no splenomegaly in any case. CONCLUSIONS Mean serum bilirubin in cases of acute viral hepatitis was 6.56 mg/dl. Mean ALT was 1202.2 U/L in cases of acute viral hepatitis
Authors and Affiliations
Pavan D. Patel, Shruti Nair, Nitin Jadhav, Aparna Patange, Patel D. M. , Amit Botre
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