Assessment of effect of computer tomography with intravenous contrast administration on renal excretory function
Journal Title: Annales Academiae Medicae Silesiensis - Year 2016, Vol 70, Issue
Abstract
INTRODUCTION: Despite the described risk of contrast-induced nephropathy, defined as sudden (up-to 48–72 h) deterioration of renal function after the administration of contrast, guidelines for border level renal excretory function markers securing safe contrast CT have not been established. The aim of study was to assess the effect of CT with intravenous contrast on changes of renal excretory function markers. MATERIALS AND METHODS: In a prospective study, 60 patients who had CT with intravenous contrast were analyzed. Before CT and after 48 hours, the level of markers of renal function: creatinine, urea and potassium were marked in the patients’ serum and the eGFR value was calculated. The patients were divided into 2 groups, depending on the output value of creatinine and eGFR: group 1 – normal values and group 2 – slightly elevated ones by 20%. RESULTS: The average concentration of creatinine before CT did not differ significantly from the values after contrast application (1.05 ± 0.23 vs. 1.03 ± 0.26 mg/dl). The average value of eGFR before contrast CT did not differ significantly from the value after contrast application (71.53 ± 18.86 vs. 74.25 ± 22.50 ml/min./1.73 m2). No significant changes in urea and potassium concentrations after radio-contrast application were observed. The values of the analyzed markers did not differ significantly compared to the baseline values in any group, nor did sex or type of CT have an effect on the marker levels. CONCLUSIONS: The intravenous administration of contrast during CT does not cause significant changes in renal excretory function markers, either in patients with normal renal function or in patients with baseline values elevated by 20%, irrespective of sex or type of CT.
Authors and Affiliations
Mikołaj Pietrzak, Grzegorz Cieślar
Keywords
Related Articles
- EP ID EP366462
- DOI 10.18794/aams/43666
- Views 89
- Downloads 0
Zmiany elektrokardiograficzne u kobiet ciężarnych i w okresie połogu
Ciąża i poród, choć należą do fizjologicznego i naturalnego czasu w życiu kobiety, wiążą się z wieloma zmianami w jej organizmie. Całkowita objętość krwi, rzut serca i tętno u kobiet w ciąży znacznie odbiegają od wartośc...
Patogeneza, profilaktyka i leczenie choroby tętnic obwodowych
Autor dokonuje przeglądu najnowszych ustaleń dotyczących etiologii, patogenezy oraz rozpoznawania i leczenia miażdżycy, a także specyfiki obranego wtórnego zespołu. Prócz przypomnienia istoty takich mechanizmów patogenet...
Large cerebello-pontine angle tumor in pregnancy – case report
A large cerebello-pontine angle tumor in pregnancy is a rare illness which is a challenge for neurosurgeons, obstetricians and anesthesiologists. The urgent treatment of the life-threatening obstructive hydrocephalus has...
Dieta wegetariańska stosowana przez kobiety w ciąży. Korzyści i zagrożenia dla matki i płodu
WSTĘP: Dietetycy podkreślają, że właściwie skomponowana dieta wegetariańska może być stosowana przez ludzi na różnych etapach ich życia. Jednak wciąż wiele osób uważa, że takie działanie może prowadzić do ujawniana się z...
Oxidative stress and enzymatic antioxidant status of blood and synovial fluid in rheumatoid arthritis patients
INTRODUCTION: Although the exact etiology of rheumatoid arthritis (RA) remains unknown, there is increasing evidence that reactive oxygen species (ROS) and oxidant/antioxidant imbalance are an important part of the patho...