Assessment of efficacy of intravenous fentanyl citrate for attenuation of hemodynamic responses during laryngoscopy and endotracheal intubation
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 2
Abstract
Introduction Laryngoscopy and intubation result in stimulation of larynx pharynx epipharynx and trachea which are extensively innervated by autonomic nervous system The parasympathetic supply is via the vagus and sympathetic supply via superior cervical ganglion To diminish hemodynamic responses to tracheal intubation Fentanyl along with hypnotic agents commonly used Keeping in mind an attempt has been made to assess the efficacy of injection fentanyl for attenuation of sympathetic response to intubationAims and objective To assess efficacy of 2microgramkg body weight fentanyl and 3 microgramkg body weight fentanyl administered before laryngoscopy and endotracheal intubation for attenuation of hemodynamicresponseMaterials and Methods 90 normotensive adult patients belonging to ASA physical status I of either sex age group of 1865 years free from inter current cardiovascular and neurological disease were posted for elective surgical procedures under general anaesthesia requiring orotracheal intubation were selected All were elective cases Three groups were made Group IControl group10 cc normal saline IV Group II 2microgramkg body weight fentanyl IV diluted to 10 cc with Distillate Water DW Group III 3 microgramkg body weight fentanyl IV diluted to 10 cc with DW Each group comprised of 30 patientsResult The rise in pulse rate in both the fentanyl groups was less and statistically significant than control group pConclusion Use of intravenous fentanyl in both doses ie 2 mcgkg as well as 3 mcgkg is safe and effective for attenuation of hemodynamic response to laryngoscopy and intubationKeywords Fentanyl Intubation Laryngoscopy Hemodynamic
Authors and Affiliations
Anuradha Suryaprakash Karande, Sangeeta Shrikant Page
Keywords
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- EP ID EP476445
- DOI 10.18231/2394-4994.2018.0032
- Views 93
- Downloads 0
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