Assessment of heart rate variability in the patients suffering with chronic pain of musculoskeletal origin
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2017, Vol 7, Issue 7
Abstract
Background: Prolonged pain of musculoskeletal origin can cause changes in autonomic outflow and thereby cardiovascular system. Various studies have been conducted showing the effect of chronic pain on heart rate variability (HRV), but the same study has not been conducted in the population of Eastern Uttar Pradesh. Aims and Objectives: This study was conducted to assess the effects of chronic pain on cardiovascular autonomic control in male cases versus male controls and female cases versus female controls. Materials and Methods: The patients were selected from the pain clinic out patient department with chronicity of >6 months duration and severity of >3 on visual analog scale. Age-sex matched controls were also selected. Electrocardiogram was recorded in the resting state and was analyzed for the HRV by using time and frequency domains. Results: In male cases, maximum RR interval, minimum RR interval, mean RR interval and in female cases, minimum RR is significantly different than male and female controls, respectively (P < 0.05). In frequency domain, low frequency/high frequency (L.F./H.F) ratio in male cases and L.F.m2 in female cases are different than male and female controls, respectively. Conclusion: The observations reveal that there is a decrease in parasympathetic activity and an increase in the sympathetic activity in the cases as compared to their age-sex matched controls leading to the shifting of sympathovagal balance toward the sympathetic side. The pattern of changes is similar, both in male cases versus male controls and female cases versus female controls with little difference in the magnitude.
Authors and Affiliations
Sanjeev K. Singh, Atanu Roy
Keywords
Related Articles
- EP ID EP290066
- DOI 10.5455/njppp.2017.7.0204803032017
- Views 83
- Downloads 0
Alcoholic extract of Azadirachta indica (Neem) root has no anticonvulsant activity in rodents
Background: Although roots of neem plant have established pharmacological activities such as analgesic, anti-inflammatory, antimicrobial, and anticarcinogenic, there are contradictory results as far as anticonvulsant act...
Effectiveness of mind maps as a self-learning tool in 1st year MBBS students of an Indian medical college
Background: The mind map (MM) is a powerful graphic technique that can be applied to improve learning and clearer thinking. MMs can be used as self-learning methods that facilitate understanding of difficult concepts. A...
Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis
Background: Ankylosing spondylitis (AS) is an autoimmune disease which leads to the involvement of skeletal, cardiac, nervous tissues, and other systemic diseases. Aims and Objectives: This study was conducted to assess...
Lipid profile, Thyroid profile and Eating behavior in Pre-hypertensive women
Background: Hypertension is a common health problem in developed countries. Individuals with systolic blood pressure (BP) between 120 and 139 mmHg or diastolic BP between 80 and 89 mmHg are categorized as prehypertensive...
Association of nutritional anemia with leukocyte and platelet counts in people of Odisha
Background: Anemia is the most common hematological disorder in the world, due to deficiency of micronutrients such as iron, Zn, Se, Cu, folic acid, and vitamins. Iron deficiency impairs immune response and bactericidal...