Assessment of microwave assisted and hydrodistllation extraction on Echinops persicus essential oils chemical composition and evaluation of its biological activity
Journal Title: Traditional Medicine Research - Year 2019, Vol 4, Issue 5
Abstract
Background: E. persicus which is well-known as Shakarook in local Persian botany and is extensively utilized in different parts of in Iran. Materials and methods: Essential oils from the aerial parts of Echinops persicus were isolated using hydrodistillation (HD) and microwave assisted hydrodistillation (MAHD) methods and the respective chemical profiles were analyzed by means of GC-MS technique. The in vitro antioxidant and antimicrobial activities of methanol extracts of E. persicus were investigated via using 2,2'-diphenyl-1-picrylhydrazyl (DPPH) assay as well as agar well-diffusion methods. The minimun inhibitory concentrations (MICs) of the methanol extracts of E. persicus against the test microorganisms were determined by the broth microdilution method. Results: GC-MS essential oils analysis shows 29 and 36 compounds constituting 91.9% and 98.2% of the total oils using HD and MAHD methods, respectively. Furthermore, the methanol extracts of E. persicus exhibited higher DPPH radical scavenging activity than vitamin C with an IC50 value of 0.42 ± 0.16 μg/mL. Moreover, the prepared methanol extracts preliminarily showed promising antimicrobial activities against S. aureus with the MIC value of 6.2 mg/mL. Conclusion: This study confirms that the methanol extract of E. persicus plant exhibits considerable antioxidant and antimicrobial properties in vitro.
Authors and Affiliations
Maryam Soori, Hossein Abbaspour, Hamid Hashemi-Moghaddam
Keywords
Related Articles
- EP ID EP49635
- DOI 10.12032/TMR20190826132
- Views 280
- Downloads 0
Advances in anti-inflammatory and immunoregulatory mechanisms of sinomenine
Sinomenine, a major active ingredient from traditional Chinese medicine Qingfengteng (Sinomenium acutum (Thunb.) Rehd.et Wils.), has been proven to have anti-inflammatory, analgesic, anti-tumor, immunomodulatory and othe...
A broad perspective on COVID-19: a global pandemic and a focus on preventive medicine
Coronavirus 2019 has become a highly infectious disease caused by severe acute respiratory syndrome coronavirus-2, a strain of novel coronavirus, which challenges millions of global healthcare facilities. Coronavirus are...
Jian-Gan-Xiao-Zhi decoction ameliorates high-fat high-carbohydrate diet-induced non-alcoholic fatty liver disease and insulin resistance by regulating the AMPK/JNK pathway
Background: Non-alcoholic fatty liver disease (NAFLD) can cause insulin resistance (IR) and diabetes. Our previous studies have demonstrated that Jian-Gan-Xiao-Zhi decoction (JGXZ) could be effective for the treatment of...
When a child is sick, can acupuncturing his/her mother cure a child's illness?
Recently, an article entitled Exploring Quantum Entanglement and Acupuncture has attracted widespread attention from medical practitioners and the media. This article was published in the November 2017 issue of Chinese A...
Research on Xijiao Dihuang Decoction suppressing platelet apoptosis in immune-mediated aplastic anemia based on mitochondrial mediated pathway
The aplastic anemia mice model was established in this study. BALB/c mice shall be treated with whole body irradiation with 60 Co-γradiation (5.5Gy, 1.1Gy/min × 5 min). then within 4 h, DBA/2 mice were injected lymphocyt...