Assessment of recovery from anaesthesia with analgesic doses of ketamine: A randomized controlled study
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 4, Issue 1
Abstract
Background: Delayed recovery or emergence can occur after general anaesthesia and it is one of the major challenges for an anesthesiologist. The time to recovery from anesthesia is affected by patient factors, anesthetic drugs, duration of surgery, and presence or lack of painful stimulation. In our study we found a higher incidence of delayed recovery from anesthesia with the use of sub-anesthetic doses of ketamine (0.5mg/kg) given during induction of general anesthesia Aims and objectives: To evaluate the recovery characteristics with the use of subanaesthetic doses of ketamine during general anaesthesia Material and Methods: One twenty adult patients of age between 18 and 45 years and of ASA grade 1 and 2 of either sex who underwent elective surgery at K. S. Hegde Medical Academy were included in the study. Patients were divided randomly into two groups of 60 patients. Groups were (a) Group KF with ketamine (0.5mg), fentanyl (2µg/kg) and propofol (2mg/kg), (b) group FP with fentanyl (2µg/kg) and propofol (2mg/kg). Recovery was assessed by modified Aldrete’s scoring system immediately at the end of surgery, 30 minutes and 1 hour after surgery Results: there was delayed recovery in group KF immediately and 30 minutes after extubation, whereas there was complete recovery after 1h in both the groups. Conclusion: addition of even a sub anaesthetic dose of ketamine during induction of general anaesthesia results in delayed recovery, this is an interesting finding as the duration of action of ketamine is short and thus further investigation is needed to confirm these observations and also to understand the underlying mechanisms.
Authors and Affiliations
Pradeep 1, Raveendra U S
Keywords
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