Assessment of retrocochlear hearing pathway activity in infants with central nervous system impairment occurring as an effect of perinatal asphyxia
Journal Title: Otolaryngologia Polska - Year 2008, Vol 62, Issue 4
Abstract
Introduction. The most often changes in the central nervous system (CNS) occurring as an effect of perinatal asphyxia are found to be hypoxic-ischemic encephalopathy (HIE) in term newborns, peri- (PVH) or intraventricular hemorrhages (IVH) and periventricular leukomalacia (PVL) in preterm neonates. Chronic hypoxia is considered to affect the brainstem in infants, especially nuclei of the hearing pathway are vulnerable to low oxygen level. The aim of the study was to carry out the objective assessment of the retrocochlear hearing pathway activity using ABR in infants with CNS impairment occurring as an effect of perinatal asphyxia, imaged during trans-fontanel ultrasonography. Material and methods. To the investigation 36 infants with HIE, IVH or PVL were included, the control group encompassed 32 born at term, health children. ABR recordings were performed in 3 months old children using Nicolet Spirit System for clicks of 85 and 80 dB nHL. Results. No differences were found between latencies of waves I and II. ABR latencies of waves III, IV, V and interpeak latencies I–III, III–V, I–V were signifi cantly delayed in InvG when compared to control patients. In conclusion, the brainstem activity in infants with CNS involvement as an effect of perinatal asphyxia is lower comparing to health children. Subclinical abnormalities as prolonged synaptic transmission of electric signal in retrocochlear auditory pathway were revealed.
Authors and Affiliations
Agnieszka Widziszowska, Grzegorz Namysłowski, Anna Genge, Agata Hajduk, Urszula Godula-Stuglik
Keywords
Related Articles
- EP ID EP51561
- DOI -
- Views 110
- Downloads 0
Expression of chosen chemokine receptors on the Thlymphocytes in children with hypertrophied adenoids with otitis media with effusion
Introduction: Chemokine receptors play a crucial role in the recruitment of leucocytes into inflamed tissue from secondary lymphoid organs. Aim of this study: was evaluation of the percentage Th (CD4+) lymphocytes with e...
Rare case of death due to suffocation following upper airways closure by a mucolaryngocoele
SUMMARY The report presents a rare case of suffocation due to upper airways obstruc-tion by a large mucolaryngocoele. The mechanism of death by suffocation was confirmed by histopathological examination of the Iungs whic...
Protezowanie tchawicy za pomocą stentów u chorych leczonych z powodu raka krtani
Introduction: Stenosis of the trachea and main bronchia can occur in patients with lung, larynx, thyroid gland, esophagus, in metastatic tumors, can be also caused by trauma and foreign bodies. Treatment in this conditio...
The late results of 4000 Hz frequency bone conduction after tympanoplasty
<br/><b>Introduction:</b> Surgical treatment of conductive hearing loss runs the risk of damage to the inner ear in the mechanism of acoustic trauma. <br/><b>Aim:</b> The aim of this study was to evaluate the function of...
Reconstruction of the Iarynx after a resection of a huge chondrosarcoma
SUMMARY Chondrosarcoma of the larynx is a rare condition of still unknown pathogenesis. This tumor occurs usually between the sixth and seventh decade of life. Forty five years old patient was admitted to the ENT Departm...