ASSESSMENT OF THERAPEUTIC EFFICACY AND SAFETY OF DELPHINIUM DENUDATUM WALL (JADWAR) AND LOCAL APPLICATION OF IRIS FLORENTINA (ROGHAN SOSAN) IN PAINFUL DIABETIC NEUROPATHY: A RANDOMISED SINGLE BLIND STANDARD CONTROLLED STUDY
Journal Title: GJRA-Global Journal For Research Analysis - Year 2018, Vol 7, Issue 8
Abstract
The current study was conducted to assess the efficacy and safety of Delphinium denudatum (Jadwar)and roghan sosan in patients with painful diabetic neuropathy. A randomised single-blind standard controlled trial was carried out on 30 diagnosed patients of painful diabetic neuropathy at National Institute of Unani Medicine Bangalore-India. After obtaining ethical clearance, 30 eligible patients were randomly allocated into test and control groups, comprising 15 patients in each group. Patients of test group were given Delphinium denudatum wall (Jadwar) 500mg in tablet form twice daily and local application of; Iris orentina (roghan sosan) on both feet twice daily. The patients of control group were given Strychnos nuxvomica (Azaraqi) 500 mg in tablet form twice daily for a period of 45 days. The subjective parameter- Visual analogue scale (VAS) was statistically analysed by applying Student's 't' test, two tailed dependent for intragroup comparison, two tailed independent for intergroup comparison and Levene's test for the homogeneity of variance. VAS showed strongly signicant difference (p<0.001) in intragroup comparison in both groups. The study revealed that test drugs appeared to be efficacious in the management of painful diabetic neuropathy and exhibited signicant effects in improvement of neuronal function. No adverse effects or toxicity has been reported during or after the trial.
Authors and Affiliations
Dr Zaffar Hussain
Keywords
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ASSESSMENT OF THERAPEUTIC EFFICACY AND SAFETY OF DELPHINIUM DENUDATUM WALL (JADWAR) AND LOCAL APPLICATION OF IRIS FLORENTINA (ROGHAN SOSAN) IN PAINFUL DIABETIC NEUROPATHY: A RANDOMISED SINGLE BLIND STANDARD CONTROLLED STUDY
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