Association of dyslipidemia in lichen planus patients at KIMS, Hubli – A case control study
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 8, Issue 2
Abstract
Background and Objective: Lichen planus (LP) is an idiopathic chronic inflammatory skin disorder where it etiopathogenesis is not fully understood. Persistent inflammation causes lipid disturbances, which precipitate the increase of cardiovascular risk. However, there are limited data about the lipid levels in LP patients and hence this study was undertaken to estimate the lipid levels in LP patients. Methods: A case control study was conducted, including 50 LP patients and 50 age and sex matched controls. Serum levels of TC (CHOD-PAP method), TAG (GPO-PAP method), and HDL-C (CHOD-PAP method) were estimated. LDL-C was calculated by Friedewala’s formula. Results: Patients with LP presented higher significant triglyceride values (182.93 vs. 113 mg⁄ dl), total cholesterol values (178.69 vs. 145.56 mg⁄ dl), LDL-C values (100.5 vs. 81.5 mg⁄ dl), and lower HDL-C values (40.36 vs. 47.6 mg⁄ dl) vs. controls. Interpretation and Conclusion: The results obtained in this study indicate the association of dyslipidemia in LP patients. Thus, dyslipidemia may play a role in its etiopathogenesis, hence, the lipid levels screening in LP patients will be useful to detect individuals at risk and start preventive treatment against the development of cardiovascular disease.
Authors and Affiliations
D R Manasa, Chandru M C, Ravi M Rathod, Vidya Kuntoji
Keywords
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- EP ID EP442156
- DOI 10.26611/1002824
- Views 208
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