Association of Serum MMP 9 Level with COPD and Healthy Control in North Indian Population
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 2
Abstract
- Background: Chronic Obstructive pulmonary disease (COPD) is an increasing cause of morbidity and mortality world-wide. MMP 9 is an acute phase reactant secreted by the liver in response to infection, inflammation or tissue damage. Methods: This case-control study was conducted on 35 healthy controls and 40 COPD patients at a tertiary care hospital in north India. MMP 9 levels were measured in serum by ELISA Kit. Results: The present study showed that mean MMP 9 levels in serum was significantly higher in COPD group as compared to control group (p<0.0001) and the levels increased with the increasing severity of the disease. Conclusion: Our study confirms that MMP 9 levels were significantly higher in COPD patients as compared to controls and their levels increased with the increasing severity of the disease. Measuring MMP 9 levels in combination with other biochemical markers can be helpful in monitoring disease outcome and management of the disease.
Authors and Affiliations
Sarika Pandey, Priyanka Gaur, Rajiv Garg, Surya Kant, Sandeep Bhattacharya, Abhishek Dubey, Zameerul Hasan
Keywords
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- EP ID EP671154
- DOI 10.21276/ijlssr.2018.4.2.15
- Views 134
- Downloads 0
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