Association of Serum Vitamin D3 and Glycated Haemoglobin in Type II Diabetes Mellitus Patients
Journal Title: Scholars International Journal of Biochemistry - Year 2018, Vol 1, Issue 4
Abstract
Type 2 Diabetes Mellitus is a major health concern globally. The total number of Diabetics is expected to reach 366 million by 2030. Efforts should also be made in preventing Diabetes Mellitus. Diabetes Mellitus, cancer, multiple sclerosis, psoriasis, cardiovascular diseases and metabolic syndrome are some of the non-skeletal diseases where Vitamin D3 deficiency has been implicated to play a vital role. Many studies indicate that calcium and Vitamin D3 homeostasis play an important role in development of Diabetes Mellitus. The Present study was carried out to evaluate the association between the levels of Vitamin D3 and Glycated Haemoglobin (HbA1c) in Type 2 diabetes mellitus. An Observational study was conducted at Shri Krishna Hospital, Karamsad between 100 cases of type 2 diabetes mellitus and 100 normal healthy controls. HbA1c and Renal Function was measured in both groups by validated instruments. Correlation between HbA1c and Vitamin D3 was calculated. In the study, Vitamin D3 deficiency was observed in 54% of cases and 68% of the controls. Mean Vitamin D3 levels were also significantly deficient in control group (p-0.02). There was a significant negative correlation between fasting blood glucose and vitamin D3 level. It concludes that in diabetic patients, there was a negative correlation between HbA1c and Vitamin D3 levels pointing that probably, Vitamin D3 deficiency as one of the cause in the possession of diabetes mellitus
Authors and Affiliations
Dr. Aruna Sharma, Dr. Gaurang. K Anandpara, Dr. N Haridas
Keywords
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