Atherogenic Dyslipidemia andits Management in Diabetes
Journal Title: Scholars Academic Journal of Pharmacy - Year 2015, Vol 4, Issue 4
Abstract
Atherogenic dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. The characteristic features of diabetic dyslipidemia are a high plasma triglyceride concentration, low HDL cholesterol concentration and increased concentration of small dense LDL-cholesterol particles. The lipid changes associated with diabetes mellitus are attributed to increased free fatty acid flux secondary to insulin resistance. In patients treated with a statin to LDL-cholesterol goals, the addition of ezetimibe, fenofibrate, niacin, or n-3 fatty acid ethyl esters may be required to correct the persistent atherogenic dyslipidemia. Keywords: Atherogenic dyslipidemia, Type 2 diabetes, Lipids, Lipoproteins, pharmacotherapy.
Authors and Affiliations
Jimimol Thomas, K. Krishnakumar, L. Panayappan
Keywords
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