Atherogenic Dyslipidemia in Diabetic Nephropathy
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2014, Vol 10, Issue 3
Abstract
Background: Dyslipidemia plays an important role in progression of kidney disease in patients of diabetes mellitus and leads to cardiovascular complications. The present study aimed to asses atherogenic lipid profile in patients of diabetes mellitus and diabetic nephropathy. Aim: To evaluate atherogenic lipid profile in patients of diabetes mellitus and diabetic nephropathy. Settings and Designs: This cross sectional study was undertaken in the Department of Biochemistry and kidney Unit, Department of Medicine and Department of Nephrology of Government Medical College and super speciality hospital Nagpur, Maharashtra. Material and Method : Total cholesterol (TC), Triglycerides(TG), High density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL), atherogenic ratio i.e. TC/HDL, LDL/HDL, was assessed in diabetes mellitus (n=50), diabetic nephropathy (n=50) and healthy individuals (n=50).Mean of biochemical parameter were compared by performing repeated measures one way ANOVA(F-test) and Post hoc multiple comparison of mean of three groups by Bonferroni t-test. Results: Values of total cholesterol, triglyceride ,LDL-C and TC/HDL, LDL/HDL were significantly higher in diabetes mellitus with diabetic nephropathy and diabetes mellitus without diabetic nephropathy but values of HDL-C (p<0.001) were significantly lower in diabetes mellitus with diabetic nephropathy and diabetes mellitus without diabetic nephropathy as compared to controls. Conclusion: Atherogenic dyslipidemia was more pronounced in diabetic nephropathy as compared to diabetes mellitus.
Authors and Affiliations
Katore Sarika D , Mahajan Bhushan H. , Fating Prasanna M. , Muddeshwar Manohar G. , Pramanik Sanjay
Extended Spectrum Beta - Lactamase Producing Escherichia coli at a Tertiary Care Hospital in Maharashtra, India: Phenotypic Detection and Antimicrobial Sensitivity Pattern.
Extended spectrum beta lactamases (ESBLs) are rapidly evolving plasmid mediated; TEM and SHV derived enzymes, capable of hydrolyzing oxyimino-cephalosporins and monobactams. Bacteria producing ESBLs remain an important c...
Assessment of present status of plant species in Otuoke macro habitat of Ogbia in Bayelsa state, Nigeria:A checklist of plant species in the study area
This study was carried out to assess the qualitative parameters of native species in Otuoke terrestrial habitat in view of the need for monitoring of plant species and enhance sustainability of the important services pro...
Comparing the efficacy of 2% diltiazem and verapamil with different concentrations in patients suffering from chronic anal fissure – A randomized double blind clinical trial from a tertiary care center
Background: Benign anorectal disorders are common and increasing in incidence. The decreasing intake in dietary fiber over the 20th century and into the 21st has contributed to a steady rise in preventable anorectal diso...
Comparative Study of Oxidative Stress in Carcinoma Breast Patients and Controls
In the scenario of increasing evidence of cancers, the aim of the study was to evaluate the role of oxidative stress in breast cancer. For that purpose, 40 carcinoma breast cases and 40 age, sex matched controls were eva...
Evaluation of rapid immuno-chromatographic test to differentiate between mycobacterium tuberculosis complex and nontuberculous mycobacteria
Background: Strategies used for the clinical management of patients with Mycobacterium tuberculosis complex (MTBC) and Nontuberculous Mycobacteria (NTM) are different, therefore, prompt detection, isolation, and discrimi...