Autoimmune Hemolytic Anemia
Journal Title: Chettinad Health City Medical Journal - Year 2017, Vol 6, Issue 2
Abstract
Autoimmune hemolytic anemia (AIHA) is caused by autoantibodies that react with Red Blood Cells. It is an uncommon entity. Even being a well-recognized entity for so many years, there are lot of difficulties regarding its diagnosis and therapies used for treatment. There are different types of autoimmune hemolytic anemia like warm antibody hemolytic anemia, cold agglutinin disease/paroxysmal cold hemoglobinuria and mixed type. The warm antibodies react at temperatures ≥37°C and cold agglutinin disease/ paroxysmal cold hemoglobinuria react at <37°C. Usually the hemolysis is extravascular. The positive direct antiglobulin (direct Coombs) test establishes the diagnosis and may suggest the cause. Treatment is usually cause dependent and includes corticosteroids, splenectomy, IV immune globulin, immunosuppressants and withdrawal of drugs.
Authors and Affiliations
Durga K, Noorul A, Aravind CS, Balaji R
Keywords
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