Autoimmune thyroiditis - Correlation of cytomorphological features and AMA titre
Journal Title: International Archives of Integrated Medicine - Year 2018, Vol 5, Issue 1
Abstract
Background: Thyroiditis is the second most common thyroid lesion next to endemic goitre diagnosed on FNA in iodine (I2) deficient areas. Aim: This study was carried out to study correlation between various cytomorphological features with anti-thyroid antibodies in cases of autoimmune thyroiditis diagnosed on FNAC. Materials and methods: This was a retrospective study carried out in a tertiary care teaching hospital. 150 cases diagnosed as autoimmune thyroiditis in a two year period from January 2010 to December 2011 formed the study group. The cytological findings and AMA tires were noted from the medical record available with the patient and also from Endocrinology department records. Results: Incidence of autoimmune thyroiditis was found to be 13.4%. Majority of the patients were females (96.7%), 53.3% of cases were seen in 21-40 years age group. In 97 patients anti-microsomal antibody titre (AMA) was available, 83 were positive i.e.85.6% positivity. Association between grade of lymphocytes, grade of thyroiditis and high L:E ratio with AMA titre was found to be statistically significant. Of the cytologically diagnosed cases of autoimmune thyroiditis, 14.4% cases showed AMA negativity. Thus FNAC remains the gold standard for the diagnosis. Conclusion: Grade of lymphocyte infiltration and grade of thyroiditis correlated well with AMA positivity. Association between high L:E ratio and AMA titre was found to be statistically significant.
Authors and Affiliations
Shweta P. Bijwe, Arunkumar D. Chopwad
A 2 year study of meningiomas in correlation with squash cytology and histopathological examination
Background: Meningiomas are common CNS tumors arising from the meningothelial cells and usual sites are intracranial, followed by intra spinal. WHO 2007 has categorised meningiomas into 3 grades. This grading helps in pr...
Diagnostic efficacy of fine needle aspiration cytology in breast lesions
Background: Carcinoma of the breast is a leading cause of death in women and needs to be evaluated at an early stage. FNAC helps in rapid diagnosis of breast lesions and their management. Objective: To study the diagnost...
Laparoscopic Adjustable Gastric Band as a Revision Surgery for Failed Vertical Gastric Sleeve or Roux-en-Y Gastric Bypass
Background: Bariatric surgery is seen as one of the most successful option for the control of morbid obesity and obesity related complications. Although, there are many surgical options available the laparoscopic vertica...
Factors affecting duration of untreated psychosis - A retrospective study done in general hospital setting
Background: Duration of the untreated psychosis has been predicted to be one of a factor which affects the outcome of disease and leading to poor prognosis in the patients. Previous studies had predicted that the longer...
The role of finasteride on perioperative bleeding in patients undergoing TURP: A randomized controlled study
Background: Benign prostatic hyperplasia (BPH) is the commonest urological condition affecting men over 50 years of age. Medical therapy is usually the first line management of BPH. Finasteride is a 5-alpha reductase inh...