Bacterial Ecology of Peritonitis in a Sub-Saharan Peritoneal Dialysis Unit
Journal Title: Journal of Urology & Nephrology - Year 2018, Vol 5, Issue 1
Abstract
Introduction: Peritonitis is a common and serious complication of Peritoneal Dialysis (PD). Peritonitis is a major cause of PD technique failure and conversion to long-term hemodialysis. After acquiring 10 years of experience with this complication, we conducted this study to determine the bacterial ecology profile of peritoneal infections in Dakar. Patients and methods: A retrospective descriptive and analytical study in PD unit of the Nephrology Department at Aristide Le Dantec University Hospital was performed during the period of 1 January 2011 to 31 December 2013. We included all patients on PD who had a peritoneal infection. Results: Seventy two (72) episodes of peritonitis were diagnosed in 51 patients with a peritonitis rate of 1 episode/21.03 patientmonths. The sex ratio was 0.6. Nephroangiosclerosis (56.87%), chronic glomerulonephritis (25.49%), and diabetic nephropathy (3.92%) were the most common causes of end stage renal disease. Among the patients who had infectious peritonitis, 50 (98.03%) were on continuous ambulatory peritoneal dialysis. Peritonitis was more common during the wet season (41 cases (56.94%)) than during the dry season (31 cases (43.06%)). The drained fluid was cloudy in 76.4%, purulent in 2.77% and clear in 20.83% of cases. The culture was negative in 21 cases and positive in 51 cases. The pathogens found were Gram-positive organisms in 60.78% and Gram negative in 39.22% of cases. Staphylococcus aureus was present in 25 patients (45.12%) and Pseudomonas aeruginosain 8 patients (17.64%). Antimicrobial susceptibility testing did not detect any multidrug resistance or vancomycin-resistant strains. Therapeutically, ciprofloxacin per OS was used as a first-line therapy in all patients (100%) and intraperitoneal ceftriaxone in 61 episodes (84.72%). The average duration of treatment was 17 ± 3 days. The treatment was favorable in 48 cases. Conclusion: Peritoneal infections remain common in our patients, mainly with Gram-positive bacilli. Prevention and better care of peritoneal infections are necessary to ensure an effective PD technique.
Authors and Affiliations
Ahmed Tall LEMRABOTT
Keywords
Related Articles
- EP ID EP496766
- DOI -
- Views 124
- Downloads 0
Secondary Vesical Calculi Formation on Non Absorbable Sutures Following Abdominal Hysterectomy: A Case Report
We report an uncommon case of a-48-year-old female presenting with calculi over suture in bladder following prior abdominal hysterectomy. The stone was fragmented and removed via transurethral cystolitholapaxy using pneu...
Handgrip Strength and Weight Predict Long-Term Mortality in Acute Kidney Injury Patients
Introduction: Surviving acute kidney (AKI) patients have a higher late mortality. The negative impact of malnutrition on the early outcome of AKI patients has recently been confirmed by various studies. However, its impa...
Pelvic and Abdominal Lipomatosis – A Rare Case Report with Atypical Presentations
Pelvic lipomatosis is defined as a condition characterized by the diffuse proliferation of normal mature fatty tissue in the perirectal and perivesical region. We present a rare case of 50 years male, normotensive, normo...
Inducing All Our ‘Low-Risk’ Transplant Candidates: Shall We Or Shall We Not?
Acute rejection episode (ARE) in an allograft recipient has a negative impact on graft survival, and therefore, preventing ARE is of paramount importance. Induction by antibody preparations is one such strategy that has...
Lower Urinary Tract Dysfunction after Radical Hysterectomy for Cervical Cancer
Despite effective screening, cervical cancer continues to be a major public health problem among women. Radical hysterectomy represents the cornerstone in the management of localized cervical cancer especially in young w...