Bacteriologic Profile and Antibiogram of the Blood Culture Isolates in Febrile Children
Journal Title: International Journal of Innovative Research in Medical Science - Year 2017, Vol 2, Issue 11
Abstract
Bacteraemia is a common condition in children with a resultant high morbidity and mortality. There are limited data on the etiology and characteristics of bloodstream infections in children. Objectives: The aim of this study was to determine the bacteriological profile and antibiotic sensitivity pattern of blood culture isolates. Methods: Blood cultures from 2831 febrile children below 15 years of age presenting to Kanti Children Hospital, Kathmandu; Nepal from June 2011 to April 2012 were examined. The growths from subcultures were identified by conventional biochemical tests and serological tests. Antibiotic susceptibility testing to antibiotics was performed by Kirby Bauer disc diffusion method. Results: The positivity of blood culture was 5% (142/2831). Gram positive and gram negative bacteria constituted 59.1% and 40.9% respectively. The most prevalent bacterial isolates were Staphylococcus aureus (52.1%) and Escherichia coli (23.2%). The study showed that the most effective drugs against S. aureus were Aamikacin and Chloramphenicol and against E. coli were Amikacin, Chloramphenicol and Ciprofloxacin. The most sensitive and preferable among the tested antibiotics was Chloramphenicol and Cephalosporins were most ineffective drugs. Conclusion: This study highlights the variable nature of antibiotic susceptibility patterns and stresses the need for continuous screening and surveillance of antibiotic resistance in pediatric care unit.
Authors and Affiliations
Shyam Prasad Pant, Dhruba Hari Chandi, Rajan Karki
Keywords
Related Articles
- EP ID EP450802
- DOI -
- Views 81
- Downloads 0
Recurrent Cardiac Myxoma with Unusual Histopathology
Recurrence of cardiac myxoma is rare, seen in about 2-3% of patients, in sporadic cases, although recurrence is frequently seen in familial type. The Authors report a case of non-familial right atrial myxoma, after succe...
Protein, Lactate Dehydrogenase and Glucose Estimation in Pleural Fluid of Tuberculosis Pleural Effusion Patients
Introduction: Tuberculosis Pleural effusion is a leading inflammatory pleural disease in clinical practice and a common public health problem related to tuberculosis. Aim: To estimate value of protein, lactate dehydrogen...
Adults Hemoglobin Level in Atiafa Primary Health Care Center in Najran Area (5-7)/1433 H
The aim of this study was to estimate hemoglobin Level among adults in Atiafa Primary Health Care Center in Najran Area, Saudi Arabia (5-7)/1433 H. A total of 90 adults were recruited of which, 48 were females and 42 wer...
DETECTION OF P16INK4A IN ORAL CAVITY AND OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
The incidence of HPV associated Head and Neck Squamous Cell Carcinoma (HNSCC) is increasing over the past 30 years. It is a growing public health concern. It has been reported that tissues of HPV associated HNSCCs over e...
Necrotizing Enterocolitis’ In Premature Neonates - The Putative Role of Early Gastrointestinal Colonization
Introduction: Necrotizing enterocolitis (NEC) is a gastrointestinal emergency and a major cause of morbidity in the neonatal intensive care unit (NICU).We studied the risk factors, pattern and type of microorganisms colo...