Bacteriological profile and antibiotic susceptibility test of blood culture isolates in pediatric patients at a tertiary care teaching hospital
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2017, Vol 3, Issue 1
Abstract
Background: Aim of the study was to know the bacterial profile and antibiotic resistance pattern of blood culture isolates from pediatric patients in at a tertiary care teaching hospital. Methods: Between March 2014– July 2015, blood culture samples from 1346 children (0-18 years) were monitored for the growth in the BACTEC/automated instrument. Samples suspicious of growth as indicated by the instrument were sub cultured and incubated at 370C and identified by standard procedure. Antibiotic susceptibility testing was performed by Kirby-Bauer disk diffusion method. Results: Out of 1346 blood culture samples processed, 159 (11.8%) were positive. Among positive isolates Salmonella species were 66.6% and non-Salmonella species were 33.3%. Predominant non-Salmonella species isolated were NFGNB (10.1%), 5% each of CoNS and Enterococcus spp. Among Salmonella spp isolated majority (85%) were S. typhi and (15%) were S. paratyphi A. isolated. The predominant isolates from ICU were NFGNB (30%), CoNS (20%) and Pseudomonas species (13.3%). Both S. typhi and S. paratyphi A revealed 18% and 19% resistance to ciprofloxacin; 8% and 19% resistance to ampicillin respectively. No resistance for chloramphenicol and ceftriaxone were noted in S. paratyphi A. Resistance of 2.2% each to chloramphenicol and cefotaxime, 5.6% to co-trimoxazole was noted, however no resistance was noted to ceftriaxone in S. typhi. Conclusion: A constant monitoring of blood cultures in pediatric age group is critical to understand bacterial profile and their antibiotic susceptibility pattern in different age groups to provide better patient care.
Authors and Affiliations
Mahesh C, Ann Mary Alex, Navaneeth BV
Keywords
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- EP ID EP305187
- DOI 10.18231/2455-6807.2017.0008
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